| 1 | Jadyn GerardiPlace 1 · Grade 11 · Anna (A.-Jonesboro) | 11 | Anna (A.-Jonesboro) | 17:53.99 |
| 2 | Caroline TepePlace 2 · Grade 12 · Okawville | 12 | Okawville | 18:13.82 |
| 3 | Gianna StassiPlace 3 · Grade 11 · Roxana | 11 | Roxana | 18:25.68 |
| 4 | Claire SkaffPlace 4 · Grade 9 · Belleville (Althoff Catholic) | 9 | Belleville (Althoff Catholic) | 18:44.84 |
| 5 | Brooke DeterdingPlace 5 · Grade 10 · New Athens | 10 | New Athens | 18:50.53 |
| 6 | Makyla SeibersPlace 6 · Grade 12 · Carmi (C.-White County) | 12 | Carmi (C.-White County) | 18:50.89 PR |
| 7 | Hadley DouglassPlace 7 · Grade 9 · Norris City (N.C.-Omaha-Enfield) | 9 | Norris City (N.C.-Omaha-Enfield) | 18:52.38 |
| 8 | Kenzie MillerPlace 8 · Grade 12 · Anna (A.-Jonesboro) | 12 | Anna (A.-Jonesboro) | 18:56.25 PR |
| 9 | Lucy DoylePlace 9 · Grade 10 · Edwardsville (Metro-East Lutheran) | 10 | Edwardsville (Metro-East Lutheran) | 18:59.67 PR |
| 10 | Raegan JonesPlace 10 · Grade 12 · Anna (A.-Jonesboro) | 12 | Anna (A.-Jonesboro) | 19:11.90 |
| 11 | Kylee MyersPlace 11 · Grade 11 · Anna (A.-Jonesboro) | 11 | Anna (A.-Jonesboro) | 19:17.08 |
| 12 | Breigh DesmondPlace 12 · Grade 11 · Belleville (Althoff Catholic) | 11 | Belleville (Althoff Catholic) | 19:20.39 |
| 13 | Sophia HillPlace 13 · Grade 10 · Anna (A.-Jonesboro) | 10 | Anna (A.-Jonesboro) | 19:24.70 |
| 14 | Nova ShawPlace 14 · Grade 9 · Roxana | 9 | Roxana | 19:28.70 |
| 15 | Camryn WheelerPlace 15 · Grade 9 · Breese (Mater Dei) | 9 | Breese (Mater Dei) | 19:29.27 |
| 16 | Lilly TuckerPlace 16 · Grade 11 · New Athens | 11 | New Athens | 19:32.56 PR |
| 17 | Grace JansenPlace 17 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 19:36.01 |
| 18 | Reese JonesPlace 18 · Grade 12 · Anna (A.-Jonesboro) | 12 | Anna (A.-Jonesboro) | 19:38.41 |
| 19 | Ava GregoryPlace 19 · Grade 12 · DuQuoin | 12 | DuQuoin | 19:38.66 PR |
| 20 | Ava WagnerPlace 20 · Grade 12 · Red Bud | 12 | Red Bud | 19:41.05 |
| 21 | Addyson PielPlace 21 · Grade 12 · Red Bud | 12 | Red Bud | 19:41.97 |
| 22 | Emeri SagerPlace 22 · Grade 10 · Fairfield | 10 | Fairfield | 19:47.78 PR |
| 23 | Ainsley TurkingtonPlace 23 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 19:52.91 |
| 24 | Colleen KingPlace 24 · Grade 10 · Vienna | 10 | Vienna | 19:53.85 PR |
| 25 | Faith JansenPlace 25 · Grade 9 · Belleville (Althoff Catholic) | 9 | Belleville (Althoff Catholic) | 20:02.91 |
| 26 | Jennie RenPlace 26 · Grade 12 · Benton | 12 | Benton | 20:02.92 PR |
| 27 | Finley HaagPlace 27 · Grade 11 · Breese (Mater Dei) | 11 | Breese (Mater Dei) | 20:06.42 |
| 28 | Kaylee GrandtPlace 28 · Grade 9 · Columbia | 9 | Columbia | 20:10.06 |
| 29 | Bella RedeniusPlace 29 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 20:10.58 PR |
| 30 | Kadence BrunoPlace 30 · Grade 10 · Pinckneyville | 10 | Pinckneyville | 20:11.33 |
| 31 | McKenzie JonesPlace 31 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 20:13.15 |
| 32 | Emma DiekemperPlace 32 · Grade 12 · Breese (Mater Dei) | 12 | Breese (Mater Dei) | 20:15.71 |
| 33 | Katelin HuelsmannPlace 33 · Grade 9 · Breese (Mater Dei) | 9 | Breese (Mater Dei) | 20:17.02 |
| 34 | Jessi BaggettPlace 34 · Grade 10 · Pinckneyville | 10 | Pinckneyville | 20:24.52 PR |
| 35 | Ava StuemkePlace 35 · Grade 12 · Murphysboro | 12 | Murphysboro | 20:27.39 |
| 36 | Addison DurbinPlace 36 · Grade 10 · Lebanon | 10 | Lebanon | 20:28.50 |
| 37 | Reagan NapovanicePlace 37 · Grade 12 · Breese (Mater Dei) | 12 | Breese (Mater Dei) | 20:29.23 |
| 38 | Carly KolesarPlace 38 · Grade 9 · Staunton | 9 | Staunton | 20:29.92 PR |
| 39 | Kaylee WolfPlace 39 · Grade 10 · Okawville | 10 | Okawville | 20:32.09 |
| 40 | Katelynn VallettPlace 40 · Grade 9 · Chester | 9 | Chester | 20:32.26 |
| 41 | Emma HoodPlace 41 · Grade 9 · McLeansboro (Hamilton County) | 9 | McLeansboro (Hamilton County) | 20:36.21 PR |
| 42 | Lillyonna Del RioPlace 42 · Grade 9 · Marissa | 9 | Marissa | 20:36.86 |
| 43 | Aniya ProctorPlace 43 · Grade 12 · Murphysboro | 12 | Murphysboro | 20:37.67 |
| 44 | Jaycie CouchPlace 44 · Grade 12 · Fairfield | 12 | Fairfield | 20:40.22 PR |
| 45 | Claira FoldenPlace 45 · Grade 11 · Pinckneyville | 11 | Pinckneyville | 20:43.48 PR |
| 46 | Elizabeth ClousePlace 46 · Grade 11 · Roxana | 11 | Roxana | 20:46.74 |
| 47 | Reid EmigPlace 47 · Grade 12 · Breese (Mater Dei) | 12 | Breese (Mater Dei) | 20:47.49 |
| 48 | Katelyn GogolekPlace 48 · Grade 10 · Okawville | 10 | Okawville | 20:47.62 |
| 49 | Karry WarehimePlace 49 · Grade 11 · Vienna | 11 | Vienna | 20:50.61 PR |
| 50 | Brianna MeeksPlace 50 · Grade 10 · Fairfield | 10 | Fairfield | 20:51.25 PR |
| 51 | Cecelia LuekePlace 51 · Grade 9 · McLeansboro (Hamilton County) | 9 | McLeansboro (Hamilton County) | 20:53.39 PR |
| 52 | Cecilia MuehlPlace 52 · Grade 10 · Columbia | 10 | Columbia | 20:53.67 |
| 53 | Savannah ClinePlace 53 · Grade 9 · Roxana | 9 | Roxana | 20:57.05 |
| 54 | Carly ChambersPlace 54 · Grade 12 · Columbia | 12 | Columbia | 20:57.12 |
| 55 | Adi HickeyPlace 55 · Grade 12 · Fairfield | 12 | Fairfield | 20:57.94 |
| 56 | Greta SnyderPlace 56 · Grade 12 · Murphysboro | 12 | Murphysboro | 21:00.57 |
| 57 | Harper EllermeyerPlace 57 · Grade 10 · Murphysboro | 10 | Murphysboro | 21:01.03 |
| 58 | Remington TaylorPlace 58 · Grade 11 · Fairfield | 11 | Fairfield | 21:01.04 |
| 59 | Maggie GoodenPlace 59 · Grade 12 · Anna (A.-Jonesboro) | 12 | Anna (A.-Jonesboro) | 21:01.83 |
| 60 | Tania RivasPlace 60 · Grade 12 · Dupo | 12 | Dupo | 21:02.58 |
| 61 | Alyssa CremerPlace 61 · Grade 11 · West Frankfort (Frankfort) | 11 | West Frankfort (Frankfort) | 21:11.68 PR |
| 62 | Eliana MuehlPlace 62 · Grade 9 · Columbia | 9 | Columbia | 21:14.30 |
| 63 | Maggie HathawayPlace 63 · Grade 12 · Harrisburg | 12 | Harrisburg | 21:15.86 PR |
| 64 | Marion HemmerPlace 64 · Grade 10 · Edwardsville (Metro-East Lutheran) | 10 | Edwardsville (Metro-East Lutheran) | 21:19.42 |
| 65 | Ava LockPlace 65 · Grade 11 · Belleville (Althoff Catholic) | 11 | Belleville (Althoff Catholic) | 21:19.70 |
| 66 | Isabella ZarantiPlace 66 · Grade 11 · Vienna | 11 | Vienna | 21:24.53 PR |
| 67 | Bailey Schallenberg-DeckerPlace 67 · Grade 11 · Roxana | 11 | Roxana | 21:31.36 |
| 68 | Naomi StaplePlace 68 · Grade 9 · Murphysboro | 9 | Murphysboro | 21:37.46 |
| 69 | Josselin MateoPlace 69 · Grade 12 · Murphysboro | 12 | Murphysboro | 21:38.16 |
| 70 | Kayden ErvinPlace 70 · Grade 9 · Metropolis (Massac County) | 9 | Metropolis (Massac County) | 21:40.62 |
| 71 | Bethany KeePlace 71 · Grade 11 · Belleville (Althoff Catholic) | 11 | Belleville (Althoff Catholic) | 21:47.20 |
| 72 | Gabrielle MartinPlace 72 · Grade 11 · Columbia | 11 | Columbia | 21:47.69 |
| 73 | Gabby ZurlienePlace 73 · Grade 10 · Fairfield | 10 | Fairfield | 21:51.64 PR |
| 74 | Poppy LarsonPlace 74 · Grade 9 · Vienna | 9 | Vienna | 22:05.51 PR |
| 75 | Zoey SwensonPlace 75 · Grade 9 · DuQuoin | 9 | DuQuoin | 22:09.97 PR |
| 76 | Kylie WheelerPlace 76 · Grade 11 · Columbia | 11 | Columbia | 22:13.45 |
| 77 | Ellanie VanwayPlace 77 · Grade 11 · Fairfield | 11 | Fairfield | 22:13.98 |
| 78 | Madison BrunsPlace 78 · Grade 12 · Pinckneyville | 12 | Pinckneyville | 22:17.75 |
| 79 | Lily WallochPlace 79 · Grade 10 · Edwardsville (Metro-East Lutheran) | 10 | Edwardsville (Metro-East Lutheran) | 22:19.40 |
| 80 | Madelyn NordikePlace 80 · Grade 12 · Trenton (Wesclin) | 12 | Trenton (Wesclin) | 22:20.53 |
| 81 | Luxie GerhardtPlace 81 · Grade 9 · Staunton | 9 | Staunton | 22:26.02 |
| 82 | Ashtyn WheelerPlace 82 · Grade 12 · Breese (Mater Dei) | 12 | Breese (Mater Dei) | 22:28.40 |
| 83 | Abigail (Abby) AyerPlace 83 · Grade 10 · Edwardsville (Metro-East Lutheran) | 10 | Edwardsville (Metro-East Lutheran) | 22:34.02 |
| 84 | Miley BadgettPlace 84 · Grade 10 · Glen Carbon (Father McGivney) | 10 | Glen Carbon (Father McGivney) | 22:40.01 |
| 85 | Bell HillebrandPlace 85 · Grade 12 · Metropolis (Massac County) | 12 | Metropolis (Massac County) | 22:41.09 |
| 86 | Mallory LucykowPlace 86 · Grade 12 · Staunton | 12 | Staunton | 22:41.96 |
| 87 | Renae FikePlace 87 · Grade 11 · Harrisburg | 11 | Harrisburg | 22:43.66 |
| 88 | Briley FletcherPlace 88 · Grade 9 · Nashville | 9 | Nashville | 22:49.10 |
| 89 | Haven BrownPlace 89 · Grade 11 · McLeansboro (Hamilton County) | 11 | McLeansboro (Hamilton County) | 22:49.17 PR |
| 90 | Alyssa WhitePlace 90 · Grade 11 · DuQuoin | 11 | DuQuoin | 22:50.05 |
| 91 | Holly GregsonPlace 91 · Grade 11 · Red Bud | 11 | Red Bud | 23:03.52 |
| 92 | Savanna McPhail-CashPlace 92 · Grade 9 · West Frankfort (Frankfort) | 9 | West Frankfort (Frankfort) | 23:03.77 |
| 93 | Leah McClellandPlace 93 · Grade 9 · Columbia | 9 | Columbia | 23:04.46 |
| 94 | Anna MoorePlace 94 · Grade 10 · Glen Carbon (Father McGivney) | 10 | Glen Carbon (Father McGivney) | 23:05.81 |
| 95 | Sophia WoodPlace 95 · Grade 11 · Okawville | 11 | Okawville | 23:09.95 |
| 96 | Catelyn ReesePlace 96 · Grade 11 · West Frankfort (Frankfort) | 11 | West Frankfort (Frankfort) | 23:14.39 |
| 97 | McCulloch MillerPlace 97 · Grade 10 · Dupo | 10 | Dupo | 23:16.13 |
| 98 | Clare CarnahanPlace 98 · Grade 9 · Red Bud | 9 | Red Bud | 23:16.51 |
| 99 | Karleigh LieferPlace 99 · Grade 10 · Red Bud | 10 | Red Bud | 23:24.53 |
| 100 | Lydia LaRosaPlace 100 · Grade 11 · Staunton | 11 | Staunton | 23:24.99 |
