| 1 | Faith WiesePlace 1 · Grade 8 · Flandreau | 8 | Flandreau | 19:41.36 |
| 2 | Jaycie BabbPlace 2 · Grade 8 · Tea Area | 8 | Tea Area | 19:43.76 |
| 3 | Maelee KrempgesPlace 3 · Grade 7 · West Central | 7 | West Central | 21:41.42 |
| 4 | Brie PetersPlace 4 · Grade 11 · Tri-Valley | 11 | Tri-Valley | 21:42.79 |
| 5 | Presley LuzePlace 5 · Grade 9 · Colman-Egan | 9 | Colman-Egan | 21:43.81 |
| 6 | Lillie EidePlace 6 · Grade 10 · Centerville | 10 | Centerville | 21:56.36 |
| 7 | Grace GannonPlace 7 · Grade 10 · Canton | 10 | Canton | 21:58.03 |
| 8 | Adisen StademPlace 8 · Grade 11 · Dell Rapids | 11 | Dell Rapids | 22:00.52 |
| 9 | Reese LuzePlace 9 · Grade 11 · Colman-Egan | 11 | Colman-Egan | 22:05.87 |
| 10 | Jerica GlasserPlace 10 · Grade 8 · Sioux Falls Christian | 8 | Sioux Falls Christian | 22:07.42 |
| 11 | Aubrey KenyonPlace 11 · Grade 10 · Tea Area | 10 | Tea Area | 22:17.14 |
| 12 | Aubrey BornsPlace 12 · Grade 8 · West Central | 8 | West Central | 22:27.30 |
| 13 | Lily KleinPlace 13 · Grade 10 · Flandreau | 10 | Flandreau | 22:29.25 |
| 14 | Tori PetersonPlace 14 · Grade 8 · Sioux Falls Christian | 8 | Sioux Falls Christian | 22:29.97 |
| 15 | Natalie-Renee SmithPlace 15 · Grade 8 · Sioux Falls Christian | 8 | Sioux Falls Christian | 22:30.72 |
| 16 | Drew CaffreyPlace 16 · Grade 10 · West Central | 10 | West Central | 22:34.07 |
| 17 | Kiley WestberryPlace 17 · Grade 7 · Flandreau | 7 | Flandreau | 22:36.32 |
| 18 | Elizabeth HockenberryPlace 18 · Grade 9 · Baltic | 9 | Baltic | 22:41.22 |
| 19 | Sadie JohnsonPlace 19 · Grade 10 · Estelline/Hendricks | 10 | Estelline/Hendricks | 22:44.41 |
| 20 | Tessa EidePlace 20 · Grade 8 · Centerville | 8 | Centerville | 22:45.46 |
| 21 | Jayla YorkPlace 21 · Grade 7 · Canton | 7 | Canton | 22:55.78 |
| 22 | Briella WettlauferPlace 22 · Grade 9 · Oldham-Ramona-Rutland | 9 | Oldham-Ramona-Rutland | 23:11.77 |
| 22 | Briella WettlauferPlace 22 · Grade 9 · Oldham-Ramona-Rutland | 9 | Oldham-Ramona-Rutland | 23:11.77 PR |
| 23 | Haley KorverPlace 23 · Grade 10 · Tea Area | 10 | Tea Area | 23:32.52 |
| 24 | Abby RhodePlace 24 · Grade 11 · Colman-Egan | 11 | Colman-Egan | 23:33.39 |
| 25 | Makala HeeschPlace 25 · Grade 10 · Garretson | 10 | Garretson | 23:36.15 |
| 26 | Hannah TerkildsenPlace 26 · Grade 11 · Sanborn Central/Woonsocket | 11 | Sanborn Central/Woonsocket | 23:39.55 |
| 27 | Elizabeth PricePlace 27 · Grade 11 · Dell Rapids | 11 | Dell Rapids | 23:40.23 |
| 28 | Rebecca HeinemanPlace 28 · Grade 9 · Flandreau | 9 | Flandreau | 23:45.91 |
| 29 | Madyn LaceyPlace 29 · Grade 8 · Dell Rapids | 8 | Dell Rapids | 23:51.09 |
| 30 | Cami WollesPlace 30 · Grade 8 · St. Mary's | 8 | St. Mary's | 23:54.50 |
| 31 | Meredith DeckerPlace 31 · Grade 8 · Tea Area | 8 | Tea Area | 23:54.84 |
| 32 | Lucy VargasPlace 32 · Grade 8 · St. Mary's | 8 | St. Mary's | 23:58.25 |
| 33 | Ellie McDonaldPlace 33 · Grade 9 · West Central | 9 | West Central | 24:00.02 |
| 34 | Lydia DeckerPlace 34 · Grade 11 · Tea Area | 11 | Tea Area | 24:03.38 |
| 35 | Johannah KobesPlace 35 · Grade 9 · Sioux Falls Christian | 9 | Sioux Falls Christian | 24:12.53 |
| 36 | Vivian KoepsellPlace 36 · Grade 10 · McCook Central/Montrose | 10 | McCook Central/Montrose | 24:16.28 |
| 37 | Addy GilbertPlace 37 · Grade 12 · St. Mary's | 12 | St. Mary's | 24:22.72 |
| 38 | Josie NelsonPlace 38 · Grade 8 · Canton | 8 | Canton | 24:27.05 |
| 39 | Sadey HoltPlace 39 · Grade 8 · Baltic | 8 | Baltic | 24:39.99 |
| 40 | Sierra KleinPlace 40 · Grade 10 · St. Mary's | 10 | St. Mary's | 24:42.74 PR |
| 41 | Peyton VanZeePlace 41 · Grade 12 · Dell Rapids | 12 | Dell Rapids | 24:51.23 |
| 42 | Elaina RhodePlace 42 · Grade 9 · Colman-Egan | 9 | Colman-Egan | 24:56.15 |
| 43 | Hailey LahrPlace 43 · Grade 8 · Flandreau | 8 | Flandreau | 25:02.24 |
| 44 | Kylee CollinsPlace 44 · Grade 8 · Canton | 8 | Canton | 25:07.73 |
| 45 | Sara SchroderPlace 45 · Grade 10 · Canton | 10 | Canton | 25:10.77 |
| 46 | Lizzy DahlPlace 46 · Grade 8 · Tri-Valley | 8 | Tri-Valley | 25:17.94 |
| 47 | Sophie EidePlace 47 · Grade 12 · Centerville | 12 | Centerville | 25:26.52 |
| 48 | Meredith LarsonPlace 48 · Grade 8 · Baltic | 8 | Baltic | 25:32.76 |
| 49 | Reese OlingerPlace 49 · Grade 12 · Flandreau | 12 | Flandreau | 25:34.80 |
| 50 | Kaitlyn SwensonPlace 50 · Grade 8 · Chester | 8 | Chester | 25:41.09 |
| 51 | Claire DagelPlace 51 · Grade 10 · Estelline/Hendricks | 10 | Estelline/Hendricks | 25:45.84 |
| 52 | Madison ReiffPlace 52 · Grade 9 · St. Mary's | 9 | St. Mary's | 25:55.27 |
| 53 | Mya DeStigterPlace 53 · Grade 8 · Dell Rapids | 8 | Dell Rapids | 26:08.40 |
| 54 | Marin RhodePlace 54 · Grade 8 · Canton | 8 | Canton | 26:48.83 |
| 55 | Jaydin MitchellPlace 55 · Grade 9 · Tea Area | 9 | Tea Area | 26:54.80 |
| 56 | Marah SchockPlace 56 · Grade 10 · McCook Central/Montrose | 10 | McCook Central/Montrose | 26:55.90 PR |
| 57 | Liz BoscheePlace 57 · Grade 8 · Sanborn Central/Woonsocket | 8 | Sanborn Central/Woonsocket | 26:59.23 |
| 58 | Cariss MontgomeryPlace 58 · Grade 12 · Dell Rapids | 12 | Dell Rapids | 27:52.71 |
| 59 | Trinity BoscheePlace 59 · Grade 12 · Sanborn Central/Woonsocket | 12 | Sanborn Central/Woonsocket | 28:15.57 |
| 60 | Emilee LindgrenPlace 60 · Grade 8 · Sanborn Central/Woonsocket | 8 | Sanborn Central/Woonsocket | 30:32.79 |