| 1 | Lydia HuffmanPlace 1 · Grade 9 · Waterloo | 9 | Waterloo | 17:26.60 |
| 2 | Katie FentonPlace 2 · Grade 9 · Highland | 9 | Highland | 19:29.60 |
| 3 | Brooklyn GiffhornPlace 3 · Grade 10 · Highland | 10 | Highland | 19:32.00 |
| 4 | Milla CryderPlace 4 · Grade 10 · Mascoutah | 10 | Mascoutah | 19:35.00 |
| 5 | Chloe MillettPlace 5 · Grade 11 · Mascoutah | 11 | Mascoutah | 19:38.80 PR |
| 6 | Ryleigh PillerPlace 6 · Grade 11 · Mascoutah | 11 | Mascoutah | 19:40.60 |
| 7 | Josie KircherPlace 7 · Grade 10 · Highland | 10 | Highland | 19:48.00 |
| 8 | Emily VogtPlace 8 · Grade 11 · Waterloo | 11 | Waterloo | 19:49.60 |
| 9 | McKenzie JonesPlace 9 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 19:59.10 PR |
| 10 | Paulette MillenderPlace 10 · Grade 11 · Belleville (East) | 11 | Belleville (East) | 20:06.50 |
| 11 | Tilly SegravesPlace 11 · Grade 9 · Belleville (West) | 9 | Belleville (West) | 20:07.60 |
| 12 | Rowan PassmorePlace 12 · Grade 11 · Highland | 11 | Highland | 20:10.20 PR |
| 13 | Layla LatourPlace 13 · Grade 9 · Mascoutah | 9 | Mascoutah | 20:14.60 |
| 14 | Sophia HelfrichPlace 14 · Grade 12 · Alton | 12 | Alton | 20:15.50 |
| 15 | Kaylee GrandtPlace 15 · Grade 9 · Columbia | 9 | Columbia | 20:16.40 |
| 16 | Bella RedeniusPlace 16 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 20:22.60 |
| 17 | Monica KlockenkemperPlace 17 · Grade 12 · Alton | 12 | Alton | 20:31.80 |
| 18 | Abby DeteringPlace 18 · Grade 10 · Mascoutah | 10 | Mascoutah | 20:35.70 |
| 19 | Morgan GreenwaldPlace 19 · Grade 9 · Highland | 9 | Highland | 20:38.50 |
| 20 | Ainsley TurkingtonPlace 20 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 20:47.40 |
| 21 | Macy JonesPlace 21 · Grade 12 · Waterloo | 12 | Waterloo | 20:56.20 |
| 22 | Vivian MarronPlace 22 · Grade 12 · Highland | 12 | Highland | 21:07.70 |
| 23 | Aliyah RehlingPlace 23 · Grade 12 · Alton | 12 | Alton | 21:09.80 |
| 24 | Autumn JacksonPlace 24 · Grade 9 · Mascoutah | 9 | Mascoutah | 21:10.00 |
| 25 | Carly ChambersPlace 25 · Grade 12 · Columbia | 12 | Columbia | 21:14.20 |
| 26 | Charley FunkPlace 26 · Grade 10 · Waterloo | 10 | Waterloo | 21:17.30 |
| 27 | Alyssa SternauPlace 27 · Grade 10 · Belleville (West) | 10 | Belleville (West) | 21:45.80 PR |
| 28 | Abcde ClimacoPlace 28 · Grade 10 · Mascoutah | 10 | Mascoutah | 21:57.40 |
| 29 | Cecilia MuehlPlace 29 · Grade 10 · Columbia | 10 | Columbia | 22:11.60 |
| 30 | Allison PruittPlace 30 · Grade 11 · Alton | 11 | Alton | 22:28.20 |
| 31 | Gabrielle MartinPlace 31 · Grade 11 · Columbia | 11 | Columbia | 22:28.40 |
| 32 | Aziza WalkerPlace 32 · Grade 11 · Belleville (East) | 11 | Belleville (East) | 22:33.70 |
| 33 | Kailee WilliamsPlace 33 · Grade 12 · Belleville (West) | 12 | Belleville (West) | 22:40.70 |
| 34 | Miley BadgettPlace 34 · Grade 10 · Glen Carbon (Father McGivney) | 10 | Glen Carbon (Father McGivney) | 22:42.60 |
| 35 | Lucy SeneczynPlace 35 · Grade 10 · Belleville (West) | 10 | Belleville (West) | 22:58.60 |
| 36 | Kylie SanchezPlace 36 · Grade 10 · Belleville (West) | 10 | Belleville (West) | 23:05.40 |
| 37 | Eliana MuehlPlace 37 · Grade 9 · Columbia | 9 | Columbia | 23:14.50 |
| 38 | Meagan ProttPlace 38 · Grade 10 · Belleville (East) | 10 | Belleville (East) | 23:34.10 |
| 39 | Norah KettlerPlace 39 · Grade 12 · Waterloo | 12 | Waterloo | 23:38.20 |
| 40 | Kylie WheelerPlace 40 · Grade 11 · Columbia | 11 | Columbia | 23:39.90 |
| 41 | Kalea TavaresPlace 41 · Grade 11 · Belleville (West) | 11 | Belleville (West) | 23:41.70 |
| 42 | Morgan JinksPlace 42 · Grade 12 · Alton | 12 | Alton | 24:22.80 |
| 43 | Phoebe RangePlace 43 · Grade 9 · Columbia | 9 | Columbia | 24:39.60 |
| 44 | Arabella SumnlersPlace 44 · Grade 10 · Glen Carbon (Father McGivney) | 10 | Glen Carbon (Father McGivney) | 24:50.00 |
| 45 | Elizabeth GenisPlace 45 · Grade 10 · Granite City | 10 | Granite City | 25:26.80 |
| 46 | Anna CaughranPlace 46 · Grade 10 · Alton | 10 | Alton | 25:36.20 |
| 47 | Jordyn KellerPlace 47 · Grade 10 · Waterloo | 10 | Waterloo | 25:40.10 |
| 48 | Briley StulcePlace 48 · Grade 9 · Valmeyer | 9 | Valmeyer | 25:42.20 |
| 49 | Maria HurtadoPlace 49 · Grade 10 · Collinsville | 10 | Collinsville | 26:22.80 PR |
| 50 | Ivana TorresPlace 50 · Grade 9 · Collinsville | 9 | Collinsville | 26:24.20 |
| 51 | Sadie DemickPlace 51 · Grade 11 · Collinsville | 11 | Collinsville | 26:30.70 |
| 52 | Esme MaloPlace 52 · Grade 9 · Collinsville | 9 | Collinsville | 26:30.80 |
| 53 | Jazmine MoncelliPlace 53 · Grade 12 · Cahokia | 12 | Cahokia | 26:54.50 |
| 54 | Ayla PetryshynPlace 54 · Grade 11 · Belleville (West) | 11 | Belleville (West) | 27:09.30 |
| 55 | Issabella Tesillos-SolisPlace 55 · Grade 11 · Collinsville | 11 | Collinsville | 27:22.30 |
| 56 | Isleny GaleanaPlace 56 · Grade 9 · Granite City | 9 | Granite City | 27:27.70 |
| 57 | Arianna SuggsPlace 57 · Grade 12 · Cahokia | 12 | Cahokia | 28:27.90 |
| 58 | Malina SimmonsPlace 58 · Grade 11 · Cahokia | 11 | Cahokia | 28:31.00 |
| 59 | Sarah KraemerPlace 59 · Grade 11 · Belleville (East) | 11 | Belleville (East) | 28:39.00 |
| 60 | Hadley RellekePlace 60 · Grade 9 · Granite City | 9 | Granite City | 29:06.40 |
| 61 | ZyAirra HoltPlace 61 · Grade 12 · Cahokia | 12 | Cahokia | 29:53.40 |
| 62 | Morgan YehlingPlace 62 · Grade 9 · Granite City | 9 | Granite City | 30:13.30 |
| 63 | Dakota BellPlace 63 · Grade 10 · Cahokia | 10 | Cahokia | 30:59.40 |
| 64 | Angelle RogersPlace 64 · Grade 12 · Cahokia | 12 | Cahokia | 31:43.90 |
| 65 | Aalana RadleyPlace 65 · Grade 12 · Cahokia | 12 | Cahokia | 35:58.20 |
