| 1 | Caroline TepePlace 1 · Grade 12 · Okawville | 12 | Okawville | 18:58.16 |
| 2 | Brooke DeterdingPlace 2 · Grade 10 · New Athens | 10 | New Athens | 19:36.43 |
| 3 | Ava GregoryPlace 3 · Grade 12 · DuQuoin | 12 | DuQuoin | 20:20.85 |
| 4 | Jennie RenPlace 4 · Grade 12 · Benton | 12 | Benton | 20:35.71 |
| 5 | Ava WagnerPlace 5 · Grade 12 · Red Bud | 12 | Red Bud | 20:44.27 |
| 6 | Lilly TuckerPlace 6 · Grade 11 · New Athens | 11 | New Athens | 20:44.29 |
| 7 | Kaylee GrandtPlace 7 · Grade 9 · Columbia | 9 | Columbia | 20:53.84 |
| 8 | Addyson PielPlace 8 · Grade 12 · Red Bud | 12 | Red Bud | 21:00.46 |
| 9 | Adi WilsonPlace 9 · Grade 12 · Nashville | 12 | Nashville | 21:12.32 |
| 10 | Jessi BaggettPlace 10 · Grade 10 · Pinckneyville | 10 | Pinckneyville | 21:16.40 |
| 11 | Kadence BrunoPlace 11 · Grade 10 · Pinckneyville | 10 | Pinckneyville | 21:18.81 |
| 12 | Katelynn VallettPlace 12 · Grade 9 · Chester | 9 | Chester | 21:21.76 |
| 13 | Carly ChambersPlace 13 · Grade 12 · Columbia | 12 | Columbia | 21:22.92 |
| 14 | Lillyonna Del RioPlace 14 · Grade 9 · Marissa | 9 | Marissa | 21:23.00 |
| 15 | Kaylee WolfPlace 15 · Grade 10 · Okawville | 10 | Okawville | 21:28.34 |
| 16 | Cecilia MuehlPlace 16 · Grade 10 · Columbia | 10 | Columbia | 21:38.80 |
| 17 | Katelyn GogolekPlace 17 · Grade 10 · Okawville | 10 | Okawville | 21:41.77 |
| 18 | Emma HoodPlace 18 · Grade 9 · McLeansboro (Hamilton County) | 9 | McLeansboro (Hamilton County) | 21:44.67 |
| 19 | Claira FoldenPlace 19 · Grade 11 · Pinckneyville | 11 | Pinckneyville | 21:46.70 |
| 20 | Ruby LeemonPlace 20 · Grade 10 · Marissa | 10 | Marissa | 21:49.88 |
| 21 | Cecelia LuekePlace 21 · Grade 9 · McLeansboro (Hamilton County) | 9 | McLeansboro (Hamilton County) | 21:53.57 |
| 22 | Hillari CowanPlace 22 · Grade 9 · Steeleville | 9 | Steeleville | 21:56.65 |
| 23 | Zelena KochPlace 23 · Grade 11 · Woodlawn | 11 | Woodlawn | 22:08.27 |
| 24 | Eliana MuehlPlace 24 · Grade 9 · Columbia | 9 | Columbia | 22:22.88 |
| 25 | Gabrielle MartinPlace 25 · Grade 11 · Columbia | 11 | Columbia | 22:37.42 |
| 26 | Alyssa WhitePlace 26 · Grade 11 · DuQuoin | 11 | DuQuoin | 22:49.01 |
| 27 | Kylie WheelerPlace 27 · Grade 11 · Columbia | 11 | Columbia | 22:53.35 |
| 28 | Zoey SwensonPlace 28 · Grade 9 · DuQuoin | 9 | DuQuoin | 22:54.89 |
| 29 | Rylan ReissPlace 29 · Grade 11 · Steeleville | 11 | Steeleville | 23:06.99 |
| 30 | Madison BrunsPlace 30 · Grade 12 · Pinckneyville | 12 | Pinckneyville | 23:15.87 |
| 31 | Briley StulcePlace 31 · Grade 9 · Valmeyer | 9 | Valmeyer | 23:41.44 |
| 32 | Allie SeiberPlace 32 · Grade 9 · Marissa | 9 | Marissa | 23:43.35 PR |
| 33 | Briley FletcherPlace 33 · Grade 9 · Nashville | 9 | Nashville | 23:47.40 |
| 34 | Adeline (Addie) RiebelingPlace 34 · Grade 9 · Waterloo (Gibault Catholic) | 9 | Waterloo (Gibault Catholic) | 23:48.85 |
| 35 | Haven BrownPlace 35 · Grade 11 · McLeansboro (Hamilton County) | 11 | McLeansboro (Hamilton County) | 23:54.28 |
| 36 | Kalyn MaynardPlace 36 · Grade 10 · Campbell Hill (Trico) | 10 | Campbell Hill (Trico) | 23:57.61 |
| 37 | Sophia WoodPlace 37 · Grade 11 · Okawville | 11 | Okawville | 24:09.26 |
| 38 | Clare CarnahanPlace 38 · Grade 9 · Red Bud | 9 | Red Bud | 24:16.27 |
| 39 | Makenna ColePlace 39 · Grade 9 · DuQuoin | 9 | DuQuoin | 24:16.75 |
| 40 | Leah McClellandPlace 40 · Grade 9 · Columbia | 9 | Columbia | 24:19.85 |
| 41 | Karleigh LieferPlace 41 · Grade 10 · Red Bud | 10 | Red Bud | 24:25.07 |
| 42 | Brooke GrohmannPlace 42 · Grade 12 · Red Bud | 12 | Red Bud | 24:36.69 |
| 43 | Holly GregsonPlace 43 · Grade 11 · Red Bud | 11 | Red Bud | 24:46.73 |
| 44 | Jessica MalonePlace 44 · Grade 12 · Nashville | 12 | Nashville | 24:57.67 |
| 45 | Caitlyn HargisPlace 45 · Grade 10 · Chester | 10 | Chester | 25:04.75 |
| 46 | Lydia HolbertPlace 46 · Grade 10 · Bluford (Webber) | 10 | Bluford (Webber) | 25:17.65 |
| 47 | Mandy PartinPlace 47 · Grade 12 · Pinckneyville | 12 | Pinckneyville | 25:23.55 |
| 48 | Emma HokenessPlace 48 · Grade 10 · Okawville | 10 | Okawville | 25:27.48 |
| 49 | Taylor StatlerPlace 49 · Grade 10 · Okawville | 10 | Okawville | 25:38.69 |
| 50 | Hannah SwineyPlace 50 · Grade 11 · DuQuoin | 11 | DuQuoin | 25:49.65 |
| 51 | Madisyn RennegarbePlace 51 · Grade 12 · Okawville | 12 | Okawville | 25:55.35 |
| 52 | Adison IchouPlace 52 · Grade 12 · DuQuoin | 12 | DuQuoin | 26:32.25 |
| 53 | Love RojekPlace 53 · Grade 11 · Pinckneyville | 11 | Pinckneyville | 26:42.48 |
| 54 | Alice BarbieriPlace 54 · Grade 10 · McLeansboro (Hamilton County) | 10 | McLeansboro (Hamilton County) | 26:42.51 |
| 55 | Natalie DolcePlace 55 · Grade 9 · Campbell Hill (Trico) | 9 | Campbell Hill (Trico) | 26:52.47 |
| 56 | Emily BowlesPlace 56 · Grade 11 · Red Bud | 11 | Red Bud | 27:00.42 PR |
| 57 | Reese ZimmermanPlace 57 · Grade 9 · McLeansboro (Hamilton County) | 9 | McLeansboro (Hamilton County) | 27:02.62 |
| 58 | Evie GagePlace 58 · Grade 9 · McLeansboro (Hamilton County) | 9 | McLeansboro (Hamilton County) | 27:11.26 |
| 59 | Ahna ColemanPlace 59 · Grade 9 · Nashville | 9 | Nashville | 27:26.83 |
| 60 | Ciara GibbsPlace 60 · Grade 9 · Marissa | 9 | Marissa | 27:30.26 |
| 61 | Mackenzie AllenPlace 61 · Grade 11 · McLeansboro (Hamilton County) | 11 | McLeansboro (Hamilton County) | 28:20.09 |
| 62 | Aja BernardinoPlace 62 · Grade 12 · Waterloo (Gibault Catholic) | 12 | Waterloo (Gibault Catholic) | 28:30.36 |
| 63 | Jacie EllisPlace 63 · Grade 10 · Nashville | 10 | Nashville | 30:31.77 |
| 64 | Taylor WhipplePlace 64 · Grade 9 · Nashville | 9 | Nashville | 32:40.83 PR |
| 65 | Gabby VausePlace 65 · Grade 12 · Waterloo (Gibault Catholic) | 12 | Waterloo (Gibault Catholic) | 32:43.37 |
