| 1 | Reilly JermynPlace 1 · Grade 10 · Orange | 10 | Orange | 19:26.7 |
| 2 | Madison PutnamPlace 2 · Grade 9 · Seaforth | 9 | Seaforth | 20:21.8 |
| 3 | Alora HoneycuttPlace 3 · Grade 12 · Carrboro | 12 | Carrboro | 20:29.0 |
| 4 | Presley PynePlace 4 · Grade 12 · Carrboro | 12 | Carrboro | 20:40.3 |
| 5 | Chloe FreemanPlace 5 · Grade 9 · Seaforth | 9 | Seaforth | 20:44.6 |
| 6 | Ava BishopPlace 6 · Grade 10 · Orange | 10 | Orange | 20:47.3 |
| 7 | Ila DiazPlace 7 · Grade 10 · Cedar Ridge | 10 | Cedar Ridge | 20:53.9 |
| 8 | Isabella Taylor-hallPlace 8 · Grade 10 · Cedar Ridge | 10 | Cedar Ridge | 21:06.2 |
| 9 | Amatha ReddyPlace 9 · Grade 9 · Orange | 9 | Orange | 21:13.5 |
| 10 | Katherine LeonardPlace 10 · Grade 12 · Seaforth | 12 | Seaforth | 21:26.9 |
| 11 | Kate FinneganPlace 11 · Grade 11 · Cedar Ridge | 11 | Cedar Ridge | 21:39.2 |
| 12 | Flynn PasquarelliPlace 12 · Grade 10 · Carrboro | 10 | Carrboro | 21:53.1 |
| 13 | Kinsey RossPlace 13 · Grade 10 · Orange | 10 | Orange | 21:57.5 |
| 14 | Irena RandPlace 14 · Grade 11 · Durham School of the Arts | 11 | Durham School of the Arts | 21:59.9 |
| 15 | Anna LongPlace 15 · Grade 12 · Durham School of the Arts | 12 | Durham School of the Arts | 22:04.0 |
| 16 | Naomi HirschPlace 16 · Grade 11 · Carrboro | 11 | Carrboro | 22:15.0 |
| 17 | Bella ReyesPlace 17 · Grade 12 · Carrboro | 12 | Carrboro | 22:18.2 |
| 18 | Gracie WhitakerPlace 18 · Grade 11 · Cedar Ridge | 11 | Cedar Ridge | 22:26.0 |
| 19 | Ayla HenryPlace 19 · Grade 10 · Cedar Ridge | 10 | Cedar Ridge | 22:31.9 |
| 20 | Eliza PorterPlace 20 · Grade 9 · Durham School of the Arts | 9 | Durham School of the Arts | 22:37.2 |
| 21 | Lillian LagardePlace 21 · Grade 12 · Carrboro | 12 | Carrboro | 22:54.0 |
| 22 | Mia BlakePlace 22 · Grade 11 · Orange | 11 | Orange | 23:04.2 |
| 23 | Ada KadwellPlace 23 · Grade 10 · Seaforth | 10 | Seaforth | 23:05.8 |
| 24 | Tallulah PapendieckPlace 24 · Grade 11 · Seaforth | 11 | Seaforth | 23:09.3 |
| 25 | Shayla MendozaPlace 25 · Grade 9 · South Granville | 9 | South Granville | 23:11.4 |
| 26 | Magnolia BolducPlace 26 · Grade 9 · Orange | 9 | Orange | 23:14.3 |
| 27 | Elaina SobusPlace 27 · Grade 10 · Cedar Ridge | 10 | Cedar Ridge | 23:23.6 |
| 28 | Abigail JohnsonPlace 28 · Grade 11 · Seaforth | 11 | Seaforth | 23:28.1 |
| 29 | Kara OstrovskyPlace 29 · Grade 10 · Durham School of the Arts | 10 | Durham School of the Arts | 23:40.3 |
| 30 | Jaidyn ThomasPlace 30 · Grade 11 · Durham School of the Arts | 11 | Durham School of the Arts | 23:41.9 |
| 31 | Jilliana LessoPlace 31 · Grade 10 · Orange | 10 | Orange | 23:48.8 |
| 32 | Genevieve KeigleyPlace 32 · Grade 11 · J.F. Webb | 11 | J.F. Webb | 24:03.9 |
| 33 | Aylin McGowanPlace 33 · Grade 12 · Carrboro | 12 | Carrboro | 24:14.1 |
| 34 | Piper GenslerPlace 34 · Grade 10 · Seaforth | 10 | Seaforth | 24:16.7 |
| 35 | Anastasia JacksonPlace 35 · Grade 9 · Durham School of the Arts | 9 | Durham School of the Arts | 24:20.3 |
| 36 | Ann WilliamsPlace 36 · Grade 10 · Cedar Ridge | 10 | Cedar Ridge | 24:20.8 |
| 37 | Alondra SerafinPlace 37 · Grade 12 · South Granville | 12 | South Granville | 24:21.3 |
| 38 | Evelyn EasonPlace 38 · Grade 11 · Durham School of the Arts | 11 | Durham School of the Arts | 25:42.6 |
| 39 | Haydee SebastianPlace 39 · Grade 12 · South Granville | 12 | South Granville | 26:15.5 |
| 40 | Kaylee SchultzPlace 40 · Grade 12 · South Granville | 12 | South Granville | 26:15.5 PR |
| 41 | Kimberly HerndandezPlace 41 · Grade 11 · J.F. Webb | 11 | J.F. Webb | 31:08.6 |
| 42 | Daisy CejaPlace 42 · Grade 11 · J.F. Webb | 11 | J.F. Webb | 31:39.8 |
| 43 | Reese KeigleyPlace 43 · Grade 9 · J.F. Webb | 9 | J.F. Webb | 33:14.2 |
| 44 | Palacious Santamaria PalaciousPlace 44 · Grade 9 · J.F. Webb | 9 | J.F. Webb | 37:14.8 PR |
| 45 | Alexa BaltazorPlace 45 · Grade 11 · J.F. Webb | 11 | J.F. Webb | 38:38.4 |
| 46 | Adriana MeridaPlace 46 · Grade 12 · South Granville | 12 | South Granville | 40:17.5 PR |
| 47 | Taniyah ByrdPlace 47 · Grade 12 · South Granville | 12 | South Granville | 40:36.7 |
| 48 | Lisa DukePlace 48 · Grade 10 · South Granville | 10 | South Granville | 40:43:0 PR |
