| 1 | Ella NighborPlace 1 · Grade 12 · Clover | 12 | Clover | 17:26.2 PR |
| 2 | Kaylee RovenstinePlace 2 · Grade 11 · Fort Mill | 11 | Fort Mill | 18:01.4 PR |
| 3 | Alivia ClevelandPlace 3 · Grade 12 · Fort Mill | 12 | Fort Mill | 18:21.5 |
| 4 | Ava JagielskiPlace 4 · Grade 12 · Clover | 12 | Clover | 18:27.8 PR |
| 5 | Lauren AllenPlace 5 · Grade 9 · Fort Mill | 9 | Fort Mill | 18:40.9 PR |
| 6 | Addison EastleyPlace 6 · Grade 9 · Nation Ford | 9 | Nation Ford | 18:42.3 PR |
| 7 | Marlee CookPlace 7 · Grade 12 · Fort Mill | 12 | Fort Mill | 18:42.4 PR |
| 8 | Haley GarciaPlace 8 · Grade 11 · Nation Ford | 11 | Nation Ford | 19:08.3 |
| 9 | Bailey NolinPlace 9 · Grade 10 · Fort Mill | 10 | Fort Mill | 19:34.0 PR |
| 10 | Eva QuintanaPlace 10 · Grade 8 · Clover | 8 | Clover | 19:44.6 |
| 11 | Grace HarveyPlace 11 · Grade 11 · Northwestern | 11 | Northwestern | 19:48.7 |
| 12 | Avery MoriartyPlace 12 · Grade 12 · Fort Mill | 12 | Fort Mill | 19:51.5 |
| 13 | Karson WoodringPlace 13 · Grade 10 · Nation Ford | 10 | Nation Ford | 19:52.1 PR |
| 14 | Nadia AndrewsPlace 14 · Grade 11 · Clover | 11 | Clover | 20:09.1 PR |
| 15 | Sara DavisPlace 15 · Grade 12 · Fort Mill | 12 | Fort Mill | 20:18.1 |
| 16 | McKinley JohnsonPlace 16 · Grade 12 · Clover | 12 | Clover | 20:22.7 PR |
| 17 | Chloe LavalPlace 17 · Grade 11 · Northwestern | 11 | Northwestern | 20:25.7 |
| 18 | Sofia GibbsPlace 18 · Grade 8 · Nation Ford | 8 | Nation Ford | 20:38.7 PR |
| 19 | Allison ArrwoodPlace 19 · Grade 11 · Northwestern | 11 | Northwestern | 20:41.3 PR |
| 20 | Elise PoskoPlace 20 · Grade 11 · Nation Ford | 11 | Nation Ford | 20:47.7 |
| 21 | Skyler LavalPlace 21 · Grade 11 · Northwestern | 11 | Northwestern | 20:50.3 PR |
| 22 | Scarlett Verdino-JenkinsPlace 22 · Grade 9 · Clover | 9 | Clover | 20:59.7 |
| 23 | Piper LumsdenPlace 23 · Grade 9 · Northwestern | 9 | Northwestern | 21:02.2 |
| 24 | Madison WilsonPlace 24 · Grade 10 · Clover | 10 | Clover | 21:07.7 PR |
| 25 | Bristol MckinnonPlace 25 · Grade 9 · Northwestern | 9 | Northwestern | 21:26.0 PR |
| 26 | Ashlyn AlosiPlace 26 · Grade 8 · Northwestern | 8 | Northwestern | 21:27.0 PR |
| 27 | Emme HerringPlace 27 · Grade 10 · Riverwalk Academy | 10 | Riverwalk Academy | 21:37.6 |
| 28 | Caroline ArdisPlace 28 · Grade 9 · Rock Hill | 9 | Rock Hill | 21:38.8 |
| 29 | Madison LittlehalePlace 29 · Grade 10 · Nation Ford | 10 | Nation Ford | 22:06.4 |
| 30 | Evy CarrollPlace 30 · Grade 10 · Riverwalk Academy | 10 | Riverwalk Academy | 22:07.5 |
| 31 | Miranda SidwellPlace 31 · Grade 12 · Nation Ford | 12 | Nation Ford | 22:16.2 PR |
| 32 | Averi YorkPlace 32 · Grade 12 · Rock Hill | 12 | Rock Hill | 23:03.4 |
| 33 | Ellie HodgesPlace 33 · Grade 9 · Rock Hill | 9 | Rock Hill | 23:11.9 PR |
| 34 | Evan HinsonPlace 34 · Grade 9 · Rock Hill | 9 | Rock Hill | 23:31.8 PR |
| 35 | Gracie FullerPlace 35 · Grade 8 · Rock Hill | 8 | Rock Hill | 23:44.5 |
| 36 | Annie CarneyPlace 36 · Grade 10 · Riverwalk Academy | 10 | Riverwalk Academy | 24:11.2 |
| 37 | Hayden ThurmanPlace 37 · Grade 11 · Riverwalk Academy | 11 | Riverwalk Academy | 24:12.9 PR |
| 38 | Kai FluckPlace 38 · Grade 11 · Riverwalk Academy | 11 | Riverwalk Academy | 24:24.3 |
| 39 | Harper DaiglePlace 39 · Grade 11 · Rock Hill | 11 | Rock Hill | 25:19.7 |
| 40 | Olivia ShaverPlace 40 · Grade 7 · Riverwalk Academy | 7 | Riverwalk Academy | 28:56.3 |
