| 1 | Susana MartinezPlace 1 · Grade 10 · West Florence | 10 | West Florence | 19:31.8 |
| 2 | Isabella CardozoPlace 2 · Grade 12 · Catawba Ridge | 12 | Catawba Ridge | 20:07.9 |
| 3 | Addison EastleyPlace 3 · Grade 9 · Nation Ford | 9 | Nation Ford | 20:17.5 |
| 4 | Haley GarciaPlace 4 · Grade 11 · Nation Ford | 11 | Nation Ford | 20:18.6 |
| 5 | Kaylanna BurroughsPlace 5 · Grade 12 · West Florence | 12 | West Florence | 20:27.3 |
| 6 | Layla HolladayPlace 6 · Grade 10 · Socastee | 10 | Socastee | 20:30.6 |
| 7 | Kylee MastPlace 7 · Grade 10 · Greenville | 10 | Greenville | 20:33.8 |
| 8 | Estella BlackwellPlace 8 · Grade 7 · Lugoff-Elgin | 7 | Lugoff-Elgin | 20:39.0 |
| 9 | Caroline DixonPlace 9 · Grade 9 · Greenville | 9 | Greenville | 20:41.6 |
| 10 | Jenna MastPlace 10 · Grade 12 · Greenville | 12 | Greenville | 20:54.2 |
| 11 | Marlee ShupingPlace 11 · Grade 10 · St James | 10 | St James | 21:10.0 |
| 12 | Jessie HicksPlace 12 · Grade 9 · Greenville | 9 | Greenville | 21:11.4 |
| 13 | Keira CookPlace 13 · Grade 10 · Eastside (SC) | 10 | Eastside (SC) | 21:14.6 |
| 14 | Lindsey KelsoPlace 14 · Grade 7 · Irmo | 7 | Irmo | 21:16.3 |
| 15 | Katie IngramPlace 15 · Grade 12 · Greenville | 12 | Greenville | 21:29.1 |
| 16 | Sophie HallPlace 16 · Grade 11 · Irmo | 11 | Irmo | 21:36.4 |
| 17 | Charlotte MetcalfPlace 17 · Grade 12 · Eastside (SC) | 12 | Eastside (SC) | 21:42.5 |
| 18 | Jenna KamaledinPlace 18 · Grade 10 · Greenwood | 10 | Greenwood | 21:44.2 |
| 19 | Emma BrilesPlace 19 · Grade 9 · Greenville | 9 | Greenville | 21:44.3 |
| 20 | Mackenzie JohnstonPlace 20 · Grade 8 · St James | 8 | St James | 21:52.7 |
| 21 | Ayla CookPlace 21 · Grade 8 · Eastside (SC) | 8 | Eastside (SC) | 21:57.0 |
| 22 | Elise PoskoPlace 22 · Grade 11 · Nation Ford | 11 | Nation Ford | 21:57.5 |
| 23 | Maryn SchubigerPlace 23 · Grade 11 · St James | 11 | St James | 21:59.2 |
| 24 | Melissa JacobsPlace 24 · Grade 8 · Irmo | 8 | Irmo | 22:02.7 |
| 25 | Kaighen RaisonPlace 25 · Grade 10 · West Florence | 10 | West Florence | 22:03.1 |
| 26 | Sadie MatticePlace 26 · Grade 10 · Greenville | 10 | Greenville | 22:18.7 |
| 27 | Alaina KilpatrickPlace 27 · Grade 12 · Catawba Ridge | 12 | Catawba Ridge | 22:20.8 |
| 28 | Harper WhitsonPlace 28 · Grade 7 · Eastside (SC) | 7 | Eastside (SC) | 22:22.2 |
| 29 | Charlotte FinleyPlace 29 · Grade 7 · Eastside (SC) | 7 | Eastside (SC) | 22:22.4 |
| 30 | Peyton LarkinsPlace 30 · Grade 9 · Greenwood | 9 | Greenwood | 22:24.0 |
| 31 | Sofia GibbsPlace 31 · Grade 8 · Nation Ford | 8 | Nation Ford | 22:27.8 |
| 32 | Natalie ChurchPlace 32 · Grade 11 · Eastside (SC) | 11 | Eastside (SC) | 22:44.3 |
| 33 | Mallory AndersonPlace 33 · Grade 10 · West Florence | 10 | West Florence | 22:45.8 |
| 34 | Kate WheelerPlace 34 · Grade 7 · Irmo | 7 | Irmo | 22:47.7 |
| 35 | Annabelle ClementePlace 35 · Grade 8 · Nation Ford | 8 | Nation Ford | 22:53.1 |
| 36 | Lucy FrechettePlace 36 · Grade 8 · Socastee | 8 | Socastee | 22:57.4 |
| 37 | Charlotte HeronPlace 37 · Grade 11 · Eastside (SC) | 11 | Eastside (SC) | 23:04.6 |
| 38 | Olivia GillespiePlace 38 · Grade 10 · Catawba Ridge | 10 | Catawba Ridge | 23:05.5 |
| 39 | Miranda SidwellPlace 39 · Grade 12 · Nation Ford | 12 | Nation Ford | 23:11.2 |
| 40 | Avery HalePlace 40 · Grade 11 · Berkeley | 11 | Berkeley | 23:17.0 |
| 41 | Emma ThistlePlace 41 · Grade 10 · Lugoff-Elgin | 10 | Lugoff-Elgin | 23:18.7 |
| 42 | Brooke BillsPlace 42 · Grade 9 · Lugoff-Elgin | 9 | Lugoff-Elgin | 23:21.7 |
| 43 | Zarah Rivera-CintronPlace 43 · Grade 9 · West Florence | 9 | West Florence | 23:23.8 |
| 44 | Isabella CaseyPlace 44 · Grade 9 · Greenwood | 9 | Greenwood | 23:29.0 |
| 45 | Sydney BeadlePlace 45 · Grade 9 · St James | 9 | St James | 23:33.8 |
| 46 | Rebecca FrentiPlace 46 · Grade 11 · Socastee | 11 | Socastee | 23:35.3 |
| 47 | Madison LittlehalePlace 47 · Grade 10 · Nation Ford | 10 | Nation Ford | 23:41.7 |
| 48 | Alia ApplegatePlace 48 · Grade 9 · Irmo | 9 | Irmo | 23:49.1 |
| 49 | Maeve BeardPlace 49 · Grade 11 · Catawba Ridge | 11 | Catawba Ridge | 23:54.3 |
| 50 | Brooke MillerPlace 50 · Grade 10 · Lugoff-Elgin | 10 | Lugoff-Elgin | 23:57.0 |
| 51 | Ayden MeekPlace 51 · Grade 10 · Greenwood | 10 | Greenwood | 23:59.6 |
| 52 | Ruby SauerPlace 52 · Grade 9 · Indian Land | 9 | Indian Land | 24:01.0 |
| 53 | Brandy BetancourtPlace 53 · Grade 11 · St James | 11 | St James | 24:08.8 |
| 54 | Kaliya AlexanderPlace 54 · Grade 10 · Socastee | 10 | Socastee | 24:17.1 |
| 55 | Ava KeeferPlace 55 · Grade 11 · St James | 11 | St James | 24:17.6 |
| 56 | Paige MayhewPlace 56 · Grade 11 · Socastee | 11 | Socastee | 24:25.8 |
| 57 | Sawyer RileyPlace 57 · Grade 8 · Lugoff-Elgin | 8 | Lugoff-Elgin | 24:38.5 |
| 58 | Olivia BoxPlace 58 · Grade 10 · Irmo | 10 | Irmo | 24:41.4 |
| 59 | Maryclaire GriffithPlace 59 · Grade 8 · Greenwood | 8 | Greenwood | 24:45.5 |
| 60 | Calie SmithPlace 60 · Grade 7 · Socastee | 7 | Socastee | 24:46.1 |
| 61 | Kylie StephensonPlace 61 · Grade 10 · West Florence | 10 | West Florence | 24:51.2 |
| 62 | Rhya LynnPlace 62 · Grade 9 · Indian Land | 9 | Indian Land | 24:53.8 |
| 63 | Charlee ArnoldPlace 63 · Grade 9 · Berkeley | 9 | Berkeley | 25:05.9 |
| 64 | Hadley CordesPlace 64 · Grade 8 · Catawba Ridge | 8 | Catawba Ridge | 25:09.8 |
| 65 | Harper HaughnPlace 65 · Grade 8 · West Florence | 8 | West Florence | 25:15.9 |
| 66 | Liana YoungPlace 66 · Grade 11 · Irmo | 11 | Irmo | 25:24.8 |
| 67 | Zadie Ann WilkersonPlace 67 · Grade 12 · Catawba Ridge | 12 | Catawba Ridge | 25:31.3 |
| 68 | Taylor WilsonPlace 68 · Grade 11 · Socastee | 11 | Socastee | 25:39.9 |
| 69 | Sarah GrahamPlace 69 · Grade 8 · Indian Land | 8 | Indian Land | 25:46.3 |
| 70 | Gabriella BiancoPlace 70 · Grade 10 · St James | 10 | St James | 25:51.4 |
| 71 | Charleigh MoorePlace 71 · Grade 9 · Indian Land | 9 | Indian Land | 25:58.1 |
| 72 | Mollie PopePlace 72 · Grade 10 · Indian Land | 10 | Indian Land | 26:00.5 |
| 73 | Lillian BrownPlace 73 · Grade 12 · Catawba Ridge | 12 | Catawba Ridge | 26:14.0 |
| 74 | Delanie PadgettPlace 74 · Grade 9 · Indian Land | 9 | Indian Land | 26:22.9 |
| 75 | Keilee TuckerPlace 75 · Grade 12 · Berkeley | 12 | Berkeley | 26:42.2 |
| 76 | Ann Kaela RuginaPlace 76 · Grade 12 · Indian Land | 12 | Indian Land | 26:51.1 |
| 77 | Charlotte QuirosPlace 77 · Grade 8 · Lugoff-Elgin | 8 | Lugoff-Elgin | 27:23.6 |
| 78 | Journey ThomasPlace 78 · Grade 9 · Berkeley | 9 | Berkeley | 27:43.2 |
| 79 | Kera MeekPlace 79 · Grade 8 · Greenwood | 8 | Greenwood | 29:47.3 |
| 80 | Nicole HernandezPlace 80 · Grade 11 · Greenwood | 11 | Greenwood | 29:59.1 |
| — | Ashlyn AlosiGrade 8 · Northwestern | 8 | Northwestern | DNS |
| — | Bristol MckinnonGrade 9 · Northwestern | 9 | Northwestern | DNS |
| — | Chloe LavalGrade 11 · Northwestern | 11 | Northwestern | DNS |
| — | Piper LumsdenGrade 9 · Northwestern | 9 | Northwestern | DNS |
