| 1 | Eva CifuniPlace 1 · Grade 8 · St. Joseph's Catholic | 8 | St. Joseph's Catholic | 18:02.8 PR |
| 2 | Corrie ReinhardtPlace 2 · Grade 12 · North Charleston | 12 | North Charleston | 18:40.5 PR |
| 3 | Sierra ConnorPlace 3 · Grade 12 · Greer Middle College Charter | 12 | Greer Middle College Charter | 18:45.2 |
| 4 | Ali HymanPlace 4 · Grade 9 · Greer Middle College Charter | 9 | Greer Middle College Charter | 19:05.2 |
| 5 | Ella HammonPlace 5 · Grade 10 · Greer Middle College Charter | 10 | Greer Middle College Charter | 19:10.9 |
| 6 | Colby DelamielleurePlace 6 · Grade 9 · Hanahan | 9 | Hanahan | 19:24.2 |
| 7 | Kendall FosterPlace 7 · Grade 11 · Christ Church Episcopal | 11 | Christ Church Episcopal | 19:40.7 |
| 8 | Camille DaughertyPlace 8 · Grade 10 · Walhalla | 10 | Walhalla | 19:43.0 |
| 9 | Lexie ShentonPlace 9 · Grade 12 · Greer Middle College Charter | 12 | Greer Middle College Charter | 19:49.1 |
| 10 | Bella MairPlace 10 · Grade 10 · Greer Middle College Charter | 10 | Greer Middle College Charter | 19:56.3 |
| 11 | Millie JohanningPlace 11 · Grade 9 · Waccamaw | 9 | Waccamaw | 19:59.8 |
| 12 | Charlotte ShewPlace 12 · Grade 9 · Christ Church Episcopal | 9 | Christ Church Episcopal | 20:03.7 |
| 13 | Olive DixonPlace 13 · Grade 11 · Fox Creek | 11 | Fox Creek | 20:08.6 PR |
| 14 | Elizabeth DorrietyPlace 14 · Grade 12 · Belton-Honea Path | 12 | Belton-Honea Path | 20:15.5 PR |
| 15 | Sutton AlexanderPlace 15 · Grade 9 · St. Joseph's Catholic | 9 | St. Joseph's Catholic | 20:18.2 |
| 16 | Lowndes SmithPlace 16 · Grade 12 · Greer Middle College Charter | 12 | Greer Middle College Charter | 20:22.5 |
| 17 | Landen PrudenPlace 17 · Grade 12 · Greer Middle College Charter | 12 | Greer Middle College Charter | 20:24.7 |
| 18 | Zarya MinesPlace 18 · Grade 12 · W J Keenan | 12 | W J Keenan | 20:35.2 PR |
| 19 | Stella PastorePlace 19 · Grade 7 · Christ Church Episcopal | 7 | Christ Church Episcopal | 20:37.3 |
| 20 | Mary Blair RogersPlace 20 · Grade 9 · Southside Christian | 9 | Southside Christian | 20:37.5 |
| 21 | Laiken RoperPlace 21 · Grade 10 · Walhalla | 10 | Walhalla | 20:53.1 |
| 22 | Alaina De nazarethPlace 22 · Grade 7 · Christ Church Episcopal | 7 | Christ Church Episcopal | 20:53.3 PR |
| 23 | Kamryn BranerPlace 23 · Grade 10 · Walhalla | 10 | Walhalla | 20:59.2 |
| 24 | Brinley StevickPlace 24 · Grade 8 · Hanahan | 8 | Hanahan | 20:59.3 |
| 25 | Katelyn BussellPlace 25 · Grade 11 · Hanahan | 11 | Hanahan | 21:02.4 |
| 26 | Stella SatterfieldPlace 26 · Grade 8 · Palmetto | 8 | Palmetto | 21:04.6 |
| 27 | Martyna MarekPlace 27 · Grade 10 · Powdersville | 10 | Powdersville | 21:05.6 |
| 28 | Peyton PeduzziPlace 28 · Grade 11 · Fox Creek | 11 | Fox Creek | 21:05.8 PR |
| 29 | Lexi DelamielleurePlace 29 · Grade 11 · Hanahan | 11 | Hanahan | 21:07.6 |
| 30 | Elara TaylorPlace 30 · Grade 9 · Mountain View Prep | 9 | Mountain View Prep | 21:10.8 |
| 31 | Odette BrownPlace 31 · Grade 10 · St. Joseph's Catholic | 10 | St. Joseph's Catholic | 21:13.6 |
| 32 | Corinne OkuleyPlace 32 · Grade 8 · St. Joseph's Catholic | 8 | St. Joseph's Catholic | 21:15.5 PR |
| 33 | Harleigh SullivanPlace 33 · Grade 8 · Aynor | 8 | Aynor | 21:21.6 |
| 34 | Sophia TzouvelekasPlace 34 · Grade 12 · Christ Church Episcopal | 12 | Christ Church Episcopal | 21:30.6 PR |
| 35 | Ava WareingPlace 35 · Grade 8 · Southside Christian | 8 | Southside Christian | 21:32.6 |
| 36 | Hannah ReinhardtPlace 36 · Grade 9 · North Charleston | 9 | North Charleston | 21:36.1 |
| 37 | Maya KryshtalowychPlace 37 · Grade 11 · Fox Creek | 11 | Fox Creek | 21:38.3 |
| 38 | Kinsley BlackPlace 38 · Grade 9 · Belton-Honea Path | 9 | Belton-Honea Path | 21:38.6 |
| 39 | Elona DarbyPlace 39 · Grade 10 · Palmetto | 10 | Palmetto | 21:45.5 |
| 40 | Sydnee CothranPlace 40 · Grade 10 · Woodruff | 10 | Woodruff | 21:47.3 |
| 41 | Marlowe PowellPlace 41 · Grade 10 · Walhalla | 10 | Walhalla | 21:49.6 |
| 42 | Madeline ForrestPlace 42 · Grade 9 · Southside Christian | 9 | Southside Christian | 21:50.9 |
| 43 | Sofie WareingPlace 43 · Grade 11 · Southside Christian | 11 | Southside Christian | 21:52.4 |
| 44 | Charlotte MilesPlace 44 · Grade 7 · Southside Christian | 7 | Southside Christian | 21:54.8 |
| 45 | Aliza MendiolaPlace 45 · Grade 10 · Walhalla | 10 | Walhalla | 22:01.7 PR |
| 46 | Beatrice HamiltonPlace 46 · Grade 12 · St. Joseph's Catholic | 12 | St. Joseph's Catholic | 22:04.7 |
| 47 | Emily HuntPlace 47 · Grade 12 · Belton-Honea Path | 12 | Belton-Honea Path | 22:06.2 |
| 48 | Lauren AlexanderPlace 48 · Grade 10 · Walhalla | 10 | Walhalla | 22:16.0 |
| 49 | Julia MeadowsPlace 49 · Grade 9 · Hanahan | 9 | Hanahan | 22:17.1 |
| 50 | Emerson LowderPlace 50 · Grade 12 · Christ Church Episcopal | 12 | Christ Church Episcopal | 22:21.1 |
| 51 | Savannah PruittPlace 51 · Grade 9 · Belton-Honea Path | 9 | Belton-Honea Path | 22:22.1 |
| 52 | Zoey Jayne LawsonPlace 52 · Grade 7 · Woodruff | 7 | Woodruff | 22:22.2 |
| 53 | Olivia CantrellPlace 53 · Grade 11 · Mountain View Prep | 11 | Mountain View Prep | 22:22.7 |
| 54 | Caitlyn LynchPlace 54 · Grade 10 · Southside Christian | 10 | Southside Christian | 22:28.5 |
| 55 | Aulbree WilliamsonPlace 55 · Grade 9 · Crescent | 9 | Crescent | 22:29.5 PR |
| 56 | Kate DawkinsPlace 56 · Grade 7 · Powdersville | 7 | Powdersville | 22:34.8 |
| 57 | Reese AbramsPlace 57 · Grade 9 · Woodruff | 9 | Woodruff | 22:37.0 |
| 58 | Lily EidellPlace 58 · Grade 12 · Fox Creek | 12 | Fox Creek | 22:38.4 PR |
| 59 | Alivia WilliamsPlace 59 · Grade 10 · Palmetto | 10 | Palmetto | 22:39.1 |
| 60 | Madeline PhilpottPlace 60 · Grade 12 · Southside Christian | 12 | Southside Christian | 22:40.1 |
| 61 | Kate PutmanPlace 61 · Grade 8 · Waccamaw | 8 | Waccamaw | 22:53.4 PR |
| 62 | Catherine MortonPlace 62 · Grade 12 · Christ Church Episcopal | 12 | Christ Church Episcopal | 22:55.5 |
| 63 | Serena TaylorPlace 63 · Grade 11 · Mountain View Prep | 11 | Mountain View Prep | 22:59.3 PR |
| 64 | Addi ClinkscalesPlace 64 · Grade 7 · Belton-Honea Path | 7 | Belton-Honea Path | 23:08.5 |
| 65 | Charleigh TroutmanPlace 65 · Grade 12 · Pendleton | 12 | Pendleton | 23:12.4 |
| 66 | Leigha ClutterPlace 66 · Grade 7 · Woodruff | 7 | Woodruff | 23:15.4 PR |
| 67 | Teagan SchaeferPlace 67 · Grade 8 · Waccamaw | 8 | Waccamaw | 23:15.9 |
| 68 | Giovanna LobatoPlace 68 · Grade 11 · Waccamaw | 11 | Waccamaw | 23:18.2 |
| 69 | Pressley PorterPlace 69 · Grade 12 · Powdersville | 12 | Powdersville | 23:19.4 |
| 70 | Evana PartainPlace 70 · Grade 12 · Crescent | 12 | Crescent | 23:23.1 |
| 71 | Lashondra BrownPlace 71 · Grade 12 · Fox Creek | 12 | Fox Creek | 23:24.6 PR |
| 72 | Camryn GregoryPlace 72 · Grade 10 · Mountain View Prep | 10 | Mountain View Prep | 23:27.6 PR |
| 73 | Liza May PerryPlace 73 · Grade 9 · St. Joseph's Catholic | 9 | St. Joseph's Catholic | 23:32.0 |
| 74 | Karis AhoPlace 74 · Grade 7 · Chapman | 7 | Chapman | 23:32.2 PR |
| 75 | Lacey BurdettePlace 75 · Grade 9 · Crescent | 9 | Crescent | 23:32.3 |
| 76 | Lydia KnightenPlace 76 · Grade 7 · Woodruff | 7 | Woodruff | 23:34.5 PR |
| 77 | Catherine LongPlace 77 · Grade 10 · Chapman | 10 | Chapman | 23:38.2 |
| 78 | Sophie AndersonPlace 78 · Grade 11 · Powdersville | 11 | Powdersville | 23:39.7 |
| 79 | Zoe KnightPlace 79 · Grade 10 · Woodruff | 10 | Woodruff | 23:40.6 PR |
| 80 | Elisea MeadowsPlace 80 · Grade 12 · Hanahan | 12 | Hanahan | 23:40.8 |
| 81 | Mithali PatelPlace 81 · Grade 10 · Walhalla | 10 | Walhalla | 23:41.3 |
| 82 | Iris FulkPlace 82 · Grade 9 · Belton-Honea Path | 9 | Belton-Honea Path | 23:53.3 |
| 83 | Kenzie PricePlace 83 · Grade 10 · Crescent | 10 | Crescent | 23:56.8 |
| 84 | Victoria RussellPlace 84 · Grade 10 · St. Joseph's Catholic | 10 | St. Joseph's Catholic | 23:58.3 |
| 85 | Ani LeckenbuschPlace 85 · Grade 9 · Powdersville | 9 | Powdersville | 23:59.0 |
| 86 | Hannah LollisPlace 86 · Grade 7 · Crescent | 7 | Crescent | 24:00.7 PR |
| 87 | Isabella WoodardPlace 87 · Grade 11 · Chapman | 11 | Chapman | 24:01.5 |
| 88 | Lanah NixPlace 88 · Grade 10 · Woodruff | 10 | Woodruff | 24:03.1 |
| 89 | Italia RichesPlace 89 · Grade 10 · Mountain View Prep | 10 | Mountain View Prep | 24:09.1 |
| 90 | Eva IurkoPlace 90 · Grade 8 · Powdersville | 8 | Powdersville | 24:10.8 |
| 91 | Lorelai ClonigerPlace 91 · Grade 8 · Pendleton | 8 | Pendleton | 24:13.1 |
| 92 | Lucile PeeblesPlace 92 · Grade 11 · Pendleton | 11 | Pendleton | 24:13.1 |
| 93 | Kiersten FosterPlace 93 · Grade 12 · Pendleton | 12 | Pendleton | 24:17.0 |
| 94 | Linaya GendenbergPlace 94 · Grade 9 · Chapman | 9 | Chapman | 24:20.4 PR |
| 95 | Della HollingsworthPlace 95 · Grade 9 · Pendleton | 9 | Pendleton | 24:22.7 |
| 96 | Leah MillwoodPlace 96 · Grade 11 · Belton-Honea Path | 11 | Belton-Honea Path | 24:37.1 |
| 97 | Giselle JorgePlace 97 · Grade 8 · Mountain View Prep | 8 | Mountain View Prep | 24:37.7 PR |
| 98 | Ava GanttPlace 98 · Grade 7 · Hanahan | 7 | Hanahan | 24:41.4 PR |
| 99 | Erica GammelPlace 99 · Grade 10 · Waccamaw | 10 | Waccamaw | 24:43.4 |
| 100 | Riley MillerPlace 100 · Grade 8 · Pendleton | 8 | Pendleton | 24:45.2 |
| 101 | Meredith TurnerPlace 101 · Grade 11 · Powdersville | 11 | Powdersville | 25:04.1 |
| 102 | Dahlia SheplerPlace 102 · Grade 9 · Fox Creek | 9 | Fox Creek | 25:15.8 PR |
| 103 | Elaina ToweryPlace 103 · Grade 8 · Palmetto | 8 | Palmetto | 25:17.7 |
| 104 | Hazel VulchPlace 104 · Grade 9 · Waccamaw | 9 | Waccamaw | 25:29.6 |
| 105 | Abigail EdwardsPlace 105 · Grade 7 · Chapman | 7 | Chapman | 25:50.9 |
| 106 | Claire WhitesidePlace 106 · Grade 10 · Waccamaw | 10 | Waccamaw | 25:58.0 |
| 107 | Ella WilcoxPlace 107 · Grade 11 · Crescent | 11 | Crescent | 26:09.1 |
| 108 | Elizabeth GreenPlace 108 · Grade 8 · Pendleton | 8 | Pendleton | 26:09.7 |
| 109 | MaryBlake HaynesPlace 109 · Grade 7 · Palmetto | 7 | Palmetto | 26:11.0 PR |
| 110 | Sophia BurgessPlace 110 · Grade 10 · Palmetto | 10 | Palmetto | 26:28.2 |
| 111 | Jayla WestPlace 111 · Grade 10 · Chapman | 10 | Chapman | 26:36.3 |
| 112 | Isabel FrazierPlace 112 · Grade 8 · Chapman | 8 | Chapman | 26:38.3 |
| 113 | Kinley PrincePlace 113 · Grade 8 · Palmetto | 8 | Palmetto | 26:43.7 |
| 114 | Kaylee CastorPlace 114 · Grade 9 · Fox Creek | 9 | Fox Creek | 27:08.5 |
| 115 | LilyAnne OverstreetPlace 115 · Grade 8 · Mountain View Prep | 8 | Mountain View Prep | 27:19.2 |