| 1 | Myla McAllisterPlace 1 · Grade 9 · Breese (Mater Dei) | 9 | Breese (Mater Dei) | 18:41.6 |
| 2 | Brooke DeterdingPlace 2 · Grade 11 · New Athens | 11 | New Athens | 19:09.8 |
| 3 | Lily KamadulskiPlace 3 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 19:18.3 |
| 4 | Mary Colette BlaxtonPlace 4 · Grade 9 · St. Louis Blue Knights Homeschool | 9 | St. Louis Blue Knights Homeschool | 19:27.0 PR |
| 5 | Claire SkaffPlace 5 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 19:30.6 |
| 6 | Kiera StilesPlace 6 · Grade 12 · St. Louis Blue Knights Homeschool | 12 | St. Louis Blue Knights Homeschool | 19:43.0 PR |
| 7 | Milla CryderPlace 7 · Grade 11 · Mascoutah | 11 | Mascoutah | 19:43.8 |
| 8 | Camryn WheelerPlace 8 · Grade 10 · Breese (Mater Dei) | 10 | Breese (Mater Dei) | 19:46.7 |
| 9 | Grace JansenPlace 9 · Grade 11 · Belleville (Althoff Catholic) | 11 | Belleville (Althoff Catholic) | 19:47.5 |
| 10 | Lucy DoylePlace 10 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 19:48.4 |
| 11 | Finley HaagPlace 11 · Grade 12 · Breese (Mater Dei) | 12 | Breese (Mater Dei) | 19:53.4 |
| 12 | Sophie KellermanPlace 12 · Grade 9 · DuQuoin | 9 | DuQuoin | 19:54.5 |
| 13 | Autumn JacksonPlace 13 · Grade 10 · Mascoutah | 10 | Mascoutah | 19:58.4 |
| 14 | Brooklyn MeierPlace 14 · Grade 10 · Okawville | 10 | Okawville | 20:01.3 |
| 15 | Love RojekPlace 15 · Grade 12 · Pinckneyville | 12 | Pinckneyville | 20:03.4 |
| 16 | Kaylee GrandtPlace 16 · Grade 10 · Columbia | 10 | Columbia | 20:05.4 |
| 17 | Faith JansenPlace 17 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 20:11.5 |
| 18 | Layla LatourPlace 18 · Grade 10 · Mascoutah | 10 | Mascoutah | 20:15.4 |
| 19 | Ryleigh PillerPlace 19 · Grade 12 · Mascoutah | 12 | Mascoutah | 20:16.2 |
| 20 | Clara NetemeyerPlace 20 · Grade 9 · Breese (Mater Dei) | 9 | Breese (Mater Dei) | 20:17.9 |
| 21 | Morrison PiaseckiPlace 21 · Grade 9 · Nashville | 9 | Nashville | 20:31.4 |
| 22 | Aubrey EversgerdPlace 22 · Grade 9 · Breese (Mater Dei) | 9 | Breese (Mater Dei) | 20:40.3 |
| 23 | Avery DamrellPlace 23 · Grade 9 · St. Louis Blue Knights Homeschool | 9 | St. Louis Blue Knights Homeschool | 20:40.9 PR |
| 24 | Ava LockPlace 24 · Grade 12 · Belleville (Althoff Catholic) | 12 | Belleville (Althoff Catholic) | 20:55.1 |
| 25 | Scout LathamPlace 25 · Grade 10 · Mascoutah | 10 | Mascoutah | 20:58.6 |
| 26 | Kaylee WolfPlace 26 · Grade 11 · Okawville | 11 | Okawville | 21:02.1 |
| 27 | Maria HoldenerPlace 27 · Grade 9 · Waterloo (Gibault Catholic) | 9 | Waterloo (Gibault Catholic) | 21:02.8 PR |
| 28 | Stella HummertPlace 28 · Grade 10 · Breese (Mater Dei) | 10 | Breese (Mater Dei) | 21:05.7 PR |
| 29 | Katelyn GogolekPlace 29 · Grade 11 · Okawville | 11 | Okawville | 21:06.4 |
| 30 | Kadence BrunoPlace 30 · Grade 11 · Pinckneyville | 11 | Pinckneyville | 21:15.7 |
| 31 | Callie JensenPlace 31 · Grade 10 · Mascoutah | 10 | Mascoutah | 21:16.4 |
| 32 | Katelin HuelsmannPlace 32 · Grade 10 · Breese (Mater Dei) | 10 | Breese (Mater Dei) | 21:22.3 |
| 33 | Marion HemmerPlace 33 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 21:25.0 |
| 34 | Cecilia MuehlPlace 34 · Grade 11 · Columbia | 11 | Columbia | 21:28.7 |
| 35 | Abigail (Abby) AyerPlace 35 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 21:41.2 |
| 36 | Ava GarbePlace 36 · Grade 9 · Lebanon | 9 | Lebanon | 21:43.4 |
| 37 | Daniya HillPlace 37 · Grade 12 · East St. Louis | 12 | East St. Louis | 21:48.1 |
| 38 | Abcde ClimacoPlace 38 · Grade 11 · Mascoutah | 11 | Mascoutah | 21:49.7 |
| 39 | Lillyonna (Lilly) DelrioPlace 39 · Grade 10 · Marissa | 10 | Marissa | 21:57.8 |
| 40 | Leah MahtaniPlace 40 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 21:58.5 |
| 41 | Eliana MuehlPlace 41 · Grade 10 · Columbia | 10 | Columbia | 22:24.4 |
| 42 | Callista BradenPlace 42 · Grade 11 · St. Louis Blue Knights Homeschool | 11 | St. Louis Blue Knights Homeschool | 22:30.5 PR |
| 43 | Hillari CowanPlace 43 · Grade 10 · Steeleville | 10 | Steeleville | 22:31.6 |
| 44 | Ja'Kayla AtkinsPlace 44 · Grade 11 · East St. Louis | 11 | East St. Louis | 22:34.6 |
| 45 | Jessi BaggettPlace 45 · Grade 11 · Pinckneyville | 11 | Pinckneyville | 22:35.9 |
| 46 | Lily WallochPlace 46 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 22:38.1 |
| 47 | Emma JaroskiPlace 47 · Grade 9 · DuQuoin | 9 | DuQuoin | 22:40.5 PR |
| 48 | Liberty FletcherPlace 48 · Grade 10 · St. Louis Blue Knights Homeschool | 10 | St. Louis Blue Knights Homeschool | 22:40.7 PR |
| 49 | Leah McClellandPlace 49 · Grade 10 · Columbia | 10 | Columbia | 22:46.8 |
| 50 | Claira FoldenPlace 50 · Grade 12 · Pinckneyville | 12 | Pinckneyville | 22:49.2 |
| 51 | Moira KruegerPlace 51 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 23:04.3 |
| 52 | Bethany KeePlace 52 · Grade 12 · Belleville (Althoff Catholic) | 12 | Belleville (Althoff Catholic) | 23:04.4 |
| 53 | Zelena KochPlace 53 · Grade 12 · Woodlawn | 12 | Woodlawn | 23:06.5 |
| 54 | Avery GiacomoPlace 54 · Grade 9 · Nashville | 9 | Nashville | 23:16.9 |
| 55 | Renae FikePlace 55 · Grade 12 · Harrisburg | 12 | Harrisburg | 23:22.6 |
| 56 | Elyana CernaPlace 56 · Grade 12 · Collinsville | 12 | Collinsville | 23:24.8 |
| 57 | Lillian CampbellPlace 57 · Grade 12 · St. Louis Blue Knights Homeschool | 12 | St. Louis Blue Knights Homeschool | 23:25.5 PR |
| 58 | Makenna ColePlace 58 · Grade 10 · DuQuoin | 10 | DuQuoin | 23:31.9 |
| 59 | Branae BrownPlace 59 · Grade 12 · East St. Louis | 12 | East St. Louis | 23:32.2 |
| 60 | Caroline StajkowskiPlace 60 · Grade 9 · Edwardsville (Metro-East Lutheran) | 9 | Edwardsville (Metro-East Lutheran) | 23:35.2 PR |
| 61 | Ruby LeemonPlace 61 · Grade 11 · Marissa | 11 | Marissa | 23:36.8 |
| 62 | Kaylie SzymanskiPlace 62 · Grade 12 · St. Louis Blue Knights Homeschool | 12 | St. Louis Blue Knights Homeschool | 23:37.0 PR |
| 63 | Aubrey CharlesPlace 63 · Grade 9 · Okawville | 9 | Okawville | 23:54.4 |
| 64 | Agnes HemmerPlace 64 · Grade 9 · Edwardsville (Metro-East Lutheran) | 9 | Edwardsville (Metro-East Lutheran) | 23:58.2 |
| 65 | Alyssa WhitePlace 65 · Grade 12 · DuQuoin | 12 | DuQuoin | 24:04.7 |
| 66 | Isabella GiacomoPlace 66 · Grade 9 · Pinckneyville | 9 | Pinckneyville | 24:05.0 |
| 67 | Lila AtkinsPlace 67 · Grade 10 · Harrisburg | 10 | Harrisburg | 24:32.5 |
| 68 | Shirlores StewartPlace 68 · Grade 12 · East St. Louis | 12 | East St. Louis | 24:43.0 |
| 69 | Riley BurtonPlace 69 · Grade 9 · Columbia | 9 | Columbia | 24:51.3 |
| 70 | Skylar PacePlace 70 · Grade 11 · Collinsville | 11 | Collinsville | 24:51.5 |
| 71 | Mercie LaxtonPlace 71 · Grade 9 · Columbia | 9 | Columbia | 25:03.5 |
| 72 | Ava VenhausPlace 72 · Grade 12 · Trenton (Wesclin) | 12 | Trenton (Wesclin) | 25:11.2 |
| 73 | Kinley PovolishPlace 73 · Grade 11 · Nashville | 11 | Nashville | 25:20.5 |
| 74 | Esme MaloPlace 74 · Grade 10 · Collinsville | 10 | Collinsville | 25:21.8 |
| 75 | Zoey SwensonPlace 75 · Grade 10 · DuQuoin | 10 | DuQuoin | 25:25.6 |
| 76 | Audrey PaynePlace 76 · Grade 10 · Collinsville | 10 | Collinsville | 25:30.8 |
| 77 | Addison AllenPlace 77 · Grade 11 · Lebanon | 11 | Lebanon | 25:30.9 |
| 78 | Hannah SwineyPlace 78 · Grade 12 · DuQuoin | 12 | DuQuoin | 25:32.9 |
| 79 | Natalie JohnsonPlace 79 · Grade 11 · Columbia | 11 | Columbia | 25:37.1 |
| 80 | Emma HokenessPlace 80 · Grade 11 · Okawville | 11 | Okawville | 25:56.1 |
| 81 | Janessa TaftPlace 81 · Grade 10 · Nashville | 10 | Nashville | 26:01.1 |
| 82 | McCulloch MillerPlace 82 · Grade 11 · Dupo | 11 | Dupo | 26:13.7 |
| 83 | Emma RieckenbergPlace 83 · Grade 9 · Steeleville | 9 | Steeleville | 26:14.1 |
| 84 | Harper WoodsPlace 84 · Grade 9 · Harrisburg | 9 | Harrisburg | 26:34.9 |
| 85 | Tinley SheltonPlace 85 · Grade 10 · Harrisburg | 10 | Harrisburg | 27:25.2 |
| 86 | Lily GassPlace 86 · Grade 10 · Okawville | 10 | Okawville | 27:27.1 |
| 87 | Ahna ColemanPlace 87 · Grade 10 · Nashville | 10 | Nashville | 28:10.5 |
| 88 | Ciara GibbsPlace 88 · Grade 10 · Marissa | 10 | Marissa | 28:11.6 |
| 89 | Maryann RussellPlace 89 · Grade 11 · Marissa | 11 | Marissa | 28:15.2 |
| 90 | Sadie DemickPlace 90 · Grade 12 · Collinsville | 12 | Collinsville | 28:21.9 |
| 91 | Keegan BrownPlace 91 · Grade 12 · Lebanon | 12 | Lebanon | 28:26.4 |
| 92 | Markayla BarnesPlace 92 · Grade 12 · East St. Louis | 12 | East St. Louis | 28:40.5 |
| 93 | Emma KnappPlace 93 · Grade 11 · DuQuoin | 11 | DuQuoin | 29:00.7 PR |
| 94 | Jasmine SpillerPlace 94 · Grade 11 · East St. Louis | 11 | East St. Louis | 29:09.3 |
| 95 | Sophia WoodPlace 95 · Grade 12 · Okawville | 12 | Okawville | 29:34.4 |
| 96 | Marlena YoungmeyerPlace 96 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 29:45.3 |
| 97 | Gracie LindseyPlace 97 · Grade 11 · Carlyle | 11 | Carlyle | 31:02.2 |
| 98 | Payton ScheitlinPlace 98 · Grade 12 · Carlyle | 12 | Carlyle | 32:39.8 |
