| 1 | Oliwia WawrzyniakPlace 1 · Grade Sr · Saint Louis | Sr | Saint Louis | 20:44.8 |
| 2 | Sydney GertsenPlace 2 · Grade Fr · Saint Louis | Fr | Saint Louis | 22:16.1 |
| 3 | Morgan YeomansPlace 3 · Grade Fr · Missouri | Fr | Missouri | 23:03.3 |
| 4 | Clara GillenPlace 4 · Grade Jr · Saint Louis | Jr | Saint Louis | 23:09.9 |
| 5 | Mallorie MetzgerPlace 5 · Grade Sr · Maryville (Mo.) | Sr | Maryville (Mo.) | 23:16.1 |
| 6 | Sophia PelligreenPlace 6 · Grade Sr · Saint Louis | Sr | Saint Louis | 23:32.0 |
| 7 | Maleah EggersPlace 7 · Grade Fr · Missouri | Fr | Missouri | 23:40.3 |
| 8 | Elissa BarnardPlace 8 · Grade Sr · Missouri | Sr | Missouri | 23:49.8 |
| 9 | Maggie ZimmermanPlace 9 · Grade Fr · Saint Louis | Fr | Saint Louis | 23:51.6 |
| 10 | Tessa BowersPlace 10 · Grade Fr · Saint Louis | Fr | Saint Louis | 24:06.4 |
| 11 | Ilene LimbergPlace 11 · Grade So · Maryville (Mo.) | So | Maryville (Mo.) | 24:10.5 |
| 12 | Tegan BishopPlace 12 · Grade Sr · Saint Louis | Sr | Saint Louis | 24:12.4 |
| 13 | Lyric FordPlace 13 · Grade Sr · Maryville (Mo.) | Sr | Maryville (Mo.) | 24:40.3 |
| 14 | Meredith DryliePlace 14 · Grade So · Saint Louis | So | Saint Louis | 24:46.0 |
| 15 | Natalie BarnardPlace 15 · Grade Jr · Missouri | Jr | Missouri | 25:15.6 |
| 16 | Hannah FatadePlace 16 · Grade So · Lincoln (Mo.) | So | Lincoln (Mo.) | 25:18.1 |
| 17 | Reagan MeyerPlace 17 · Grade Fr · Saint Louis | Fr | Saint Louis | 26:16.5 PR |
| 18 | Riley FranzPlace 18 · Grade Sr · Saint Louis | Sr | Saint Louis | 26:18.8 |
| 19 | Miley JacksonPlace 19 · Grade Fr · St. Charles (Mo.) CC | Fr | St. Charles (Mo.) CC | 26:37.2 PR |
| 20 | Margaretha GrabskePlace 20 · Grade So · Saint Louis | So | Saint Louis | 26:44.7 |
| 21 | Lily GinsbergPlace 21 · Grade So · Missouri | So | Missouri | 27:20.4 |
| 22 | Sylvia CharltonPlace 22 · Grade Fr · Maryville (Mo.) | Fr | Maryville (Mo.) | 27:44.4 PR |
| 23 | Jeneail HenryPlace 23 · Grade So · Lincoln (Mo.) | So | Lincoln (Mo.) | 28:17.5 |
| 24 | Nina MartinezPlace 24 · Grade Jr · Principia | Jr | Principia | 28:26.3 |
| 25 | Violet HillPlace 25 · Grade So · Webster | So | Webster | 29:43.0 |
| 26 | Moya JeffersonPlace 26 · Grade Fr · Maryville (Mo.) | Fr | Maryville (Mo.) | 29:54.2 |
| 27 | Hannah CharlesPlace 27 · Grade So · Lincoln (Mo.) | So | Lincoln (Mo.) | 30:26.7 |
| 28 | Lydia ImbodenPlace 28 · Grade So · Webster | So | Webster | 30:31.3 |
| 29 | Lily HohnerPlace 29 · Grade Fr · Principia | Fr | Principia | 30:56.2 |
| 30 | Natalie GillPlace 30 · Grade So · St. Charles (Mo.) CC | So | St. Charles (Mo.) CC | 31:40.1 PR |
| 31 | Brooklynn LeeperPlace 31 · Grade Fr · Webster | Fr | Webster | 31:48.8 |
| 32 | Ayanna LyonsPlace 32 · Grade Fr · Webster | Fr | Webster | 32:28.8 |
| 33 | Odeshia NantonPlace 33 · Grade Sr · Lincoln (Mo.) | Sr | Lincoln (Mo.) | 32:47.6 |
| 34 | Selene AhlersmeyerPlace 34 · Grade Fr · Webster | Fr | Webster | 33:19.1 |
| 35 | Ezthia MaycockPlace 35 · Grade Sr · Lincoln (Mo.) | Sr | Lincoln (Mo.) | 33:27.8 |
| 36 | Brie InmanPlace 36 · Grade Jr · Webster | Jr | Webster | 34:12.3 |
| 37 | Rileigh ThomasPlace 37 · Grade Fr · St. Charles (Mo.) CC | Fr | St. Charles (Mo.) CC | 35:13.5 PR |
| 38 | Malika CountainPlace 38 · Grade Fr · Lincoln (Mo.) | Fr | Lincoln (Mo.) | 37:40.7 |
| 39 | Marissa UsherPlace 39 · Grade Fr · Webster | Fr | Webster | 43:14.1 |
| — | Eman ElsayedGrade Fr · Webster | Fr | Webster | DNF |
| — | Quintasia EvansGrade Fr · Principia | Fr | Principia | DNF |
| — | Fatimah AlmamoriGrade Sr · Maryville (Mo.) | Sr | Maryville (Mo.) | DNF |
| — | Starr ScottGrade Sr · Saint Louis | Sr | Saint Louis | DNF |
