| 1 | Zoey ElliottPlace 1 · Grade 12 · Salem | 12 | Salem | 21:39.6 |
| 2 | Aidan LawlerPlace 2 · Grade 10 · Pacific | 10 | Pacific | 22:28.1 |
| 3 | Adalei PerkinsPlace 3 · Grade 10 · Steelville | 10 | Steelville | 23:10.2 |
| 4 | Zoe DawsonPlace 4 · Grade 9 · West County | 9 | West County | 23:19.9 |
| 5 | Aubree LansingPlace 5 · Grade 9 · West County | 9 | West County | 23:44.5 |
| 6 | Ella BashamPlace 6 · Grade 11 · Cuba | 11 | Cuba | 23:54.6 |
| 7 | Tallulah ClackPlace 7 · Grade 9 · West County | 9 | West County | 24:02.3 |
| 8 | Shianne BrinsonPlace 8 · Grade 12 · Pacific | 12 | Pacific | 24:06.7 |
| 9 | Sophia NeubertPlace 9 · Grade 10 · Vienna | 10 | Vienna | 24:14.2 |
| 10 | Gwyneth Van LeerPlace 10 · Grade 9 · Washington | 9 | Washington | 24:16.9 |
| 11 | Elisabeth WardenPlace 11 · Grade 10 · Steelville | 10 | Steelville | 24:18.2 |
| 12 | Breauna StotlerPlace 12 · Grade 10 · Dixon | 10 | Dixon | 24:28.4 |
| 13 | Isabella FerrarioPlace 13 · Grade 11 · Pacific | 11 | Pacific | 24:30.8 |
| 14 | Sara BadePlace 14 · Grade 11 · Washington | 11 | Washington | 24:44.9 |
| 15 | River JohnsonPlace 15 · Grade 10 · Washington | 10 | Washington | 24:52.5 |
| 16 | Gabrielle BrannanPlace 16 · Grade 12 · Pacific | 12 | Pacific | 24:53.1 |
| 17 | Briley TurnerPlace 17 · Grade 9 · Valley | 9 | Valley | 25:08.1 |
| 18 | Dixie MayfieldPlace 18 · Grade 10 · Pacific | 10 | Pacific | 25:18.0 |
| 19 | Isabel DelvallePlace 19 · Grade 9 · Dixon | 9 | Dixon | 25:23.6 |
| 20 | Jaelynn PolittePlace 20 · Grade 9 · West County | 9 | West County | 25:28.5 |
| 21 | Brooke SchoonoverPlace 21 · Grade 12 · Washington | 12 | Washington | 25:30.1 |
| 22 | Abigail McCleavePlace 22 · Grade 10 · Washington | 10 | Washington | 25:32.3 |
| 23 | Ellanor KentPlace 23 · Grade 11 · Belle | 11 | Belle | 25:43.2 |
| 24 | Wyntr YatesPlace 24 · Grade 9 · Steelville | 9 | Steelville | 26:16.2 |
| 25 | Alayna RivesPlace 25 · Grade 10 · Washington | 10 | Washington | 26:32.9 |
| 26 | Adalyne HashPlace 26 · Grade 11 · St. James | 11 | St. James | 26:46.7 |
| 27 | Arianna LeePlace 27 · Grade 9 · Pacific | 9 | Pacific | 26:49.0 |
| 28 | Aleah WestPlace 28 · Grade 9 · St. Paul Lutheran (Farmington) | 9 | St. Paul Lutheran (Farmington) | 27:39.0 |
| 29 | Sarah HalcombPlace 29 · Grade 10 · Pacific | 10 | Pacific | 27:42.8 |
| 30 | Skylar StevensPlace 30 · Grade 9 · Belle | 9 | Belle | 27:57.5 |
| 31 | Ava MeisterPlace 31 · Grade 11 · St. James | 11 | St. James | 28:43.9 |
| 32 | Liliana EsparzaPlace 32 · Grade 9 · Pacific | 9 | Pacific | 28:44.2 |
| 33 | Saira RosalesPlace 33 · Grade 12 · Pacific | 12 | Pacific | 29:01.4 |
| 34 | Desiray CrookPlace 34 · Grade 11 · Licking | 11 | Licking | 29:15.7 PR |
| 35 | Reese BellPlace 35 · Grade 11 · Bourbon | 11 | Bourbon | 29:19.7 |
| 36 | Josey MartinPlace 36 · Grade 9 · Bunker | 9 | Bunker | 29:36.6 |
| 37 | Kylie VaughnPlace 37 · Grade 9 · Pacific | 9 | Pacific | 29:54.5 |
| 38 | Marianne FrancisPlace 38 · Grade 9 · Belle | 9 | Belle | 29:58.2 |
| 39 | Seyrena CarterPlace 39 · Grade 12 · Licking | 12 | Licking | 31:27.4 PR |
| 40 | Alaina EvansPlace 40 · Grade 9 · Bourbon | 9 | Bourbon | 31:53.9 |
| 41 | Allania MoorePlace 41 · Grade 11 · Belle | 11 | Belle | 31:58.0 |
| 42 | Leah NegrettiPlace 42 · Grade 12 · Bourbon | 12 | Bourbon | 32:00.5 |
| 43 | Abigail TerrillPlace 43 · Grade 12 · Salem | 12 | Salem | 32:09.8 |
| 44 | Lillian WilliamsPlace 44 · Grade 10 · Vienna | 10 | Vienna | 32:33.9 |
| 45 | Beatrice HoveyPlace 45 · Grade 12 · Salem | 12 | Salem | 32:40.7 |
| 46 | Kenadie BaileyPlace 46 · Grade 11 · Belle | 11 | Belle | 33:15.5 |
| 47 | Stormee YatesPlace 47 · Grade 10 · Steelville | 10 | Steelville | 33:24.6 |
| 48 | Savannah BeardPlace 48 · Grade 10 · Salem | 10 | Salem | 34:12.8 |
| 49 | Sedora CarrollPlace 49 · Grade 9 · Belle | 9 | Belle | 34:45.4 |
| 50 | Lainey MagnerPlace 50 · Grade 12 · Vienna | 12 | Vienna | 35:47.3 |
| 51 | Saylor KentPlace 51 · Grade 12 · Belle | 12 | Belle | 37:08.7 |
| 52 | Clara CooperPlace 52 · Grade 12 · Salem | 12 | Salem | 38:46.3 |
| 53 | Danica GarnerPlace 53 · Grade 11 · Salem | 11 | Salem | 38:52.5 |
| 54 | Jhonine MaralitPlace 54 · Grade 12 · Salem | 12 | Salem | 39:23.6 |
| 55 | Delaney GanPlace 55 · Grade 10 · Crocker | 10 | Crocker | 39:25.6 |
| 56 | Naomi ClarkPlace 56 · Grade 12 · Vienna | 12 | Vienna | 40:29.3 |
| 57 | Ariel CalvinPlace 57 · Grade 9 · Pacific | 9 | Pacific | 42:43.1 |
| 58 | Chloe LukePlace 58 · Grade 12 · Missouri School for the Deaf | 12 | Missouri School for the Deaf | 43:17.3 |
| 59 | Mikayla KuehnePlace 59 · Grade 10 · Missouri School for the Deaf | 10 | Missouri School for the Deaf | 59:46.9 |
