| 1 | Lily KamadulskiPlace 1 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 18:21.17 PR |
| 2 | Claire SkaffPlace 2 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 19:06.63 |
| 3 | Grace JansenPlace 3 · Grade 11 · Belleville (Althoff Catholic) | 11 | Belleville (Althoff Catholic) | 19:25.40 |
| 4 | Lucy DoylePlace 4 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 19:29.73 |
| 5 | Leah MahtaniPlace 5 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 19:37.50 PR |
| 6 | Elizabeth MollPlace 6 · Grade 9 · Glen Carbon (Father McGivney) | 9 | Glen Carbon (Father McGivney) | 19:45.01 PR |
| 7 | Faith JansenPlace 7 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 20:09.34 |
| 8 | Breigh DesmondPlace 8 · Grade 12 · Belleville (Althoff Catholic) | 12 | Belleville (Althoff Catholic) | 20:13.17 |
| 9 | Abigail (Abby) AyerPlace 9 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 20:14.93 PR |
| 10 | Ainsley TurkingtonPlace 10 · Grade 12 · Glen Carbon (Father McGivney) | 12 | Glen Carbon (Father McGivney) | 20:16.83 |
| 11 | Bella RedeniusPlace 11 · Grade 12 · Glen Carbon (Father McGivney) | 12 | Glen Carbon (Father McGivney) | 20:22.76 |
| 12 | McKenzie JonesPlace 12 · Grade 12 · Glen Carbon (Father McGivney) | 12 | Glen Carbon (Father McGivney) | 20:51.97 |
| 13 | Marion HemmerPlace 13 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 20:55.85 |
| 14 | Ava LockPlace 14 · Grade 12 · Belleville (Althoff Catholic) | 12 | Belleville (Althoff Catholic) | 21:01.10 |
| 15 | Moira KruegerPlace 15 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 21:32.83 PR |
| 16 | Lily WallochPlace 16 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 22:07.52 PR |
| 17 | Bethany KeePlace 17 · Grade 12 · Belleville (Althoff Catholic) | 12 | Belleville (Althoff Catholic) | 22:25.86 |
| 18 | Caroline CardinalPlace 18 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 22:37.48 PR |
| 19 | Evelyn SchultzPlace 19 · Grade 9 · Belleville (Althoff Catholic) | 9 | Belleville (Althoff Catholic) | 22:59.43 PR |
| 20 | Anna MoorePlace 20 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 23:03.68 |
| 21 | Agnes HemmerPlace 21 · Grade 9 · Edwardsville (Metro-East Lutheran) | 9 | Edwardsville (Metro-East Lutheran) | 23:14.15 PR |
| 22 | Mackenzie HobsonPlace 22 · Grade 12 · Belleville (Althoff Catholic) | 12 | Belleville (Althoff Catholic) | 25:15.83 |
| 23 | Livy PackerPlace 23 · Grade 9 · Edwardsville (Metro-East Lutheran) | 9 | Edwardsville (Metro-East Lutheran) | 25:26.28 PR |
| 24 | Isabel StabinskyPlace 24 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 25:33.80 |
| 25 | Averie StollePlace 25 · Grade 10 · Edwardsville (Metro-East Lutheran) | 10 | Edwardsville (Metro-East Lutheran) | 26:14.75 PR |
| 26 | Kaitlyn PickerellPlace 26 · Grade 12 · Edwardsville (Metro-East Lutheran) | 12 | Edwardsville (Metro-East Lutheran) | 27:05.29 |
| 27 | Hannah RaycraftPlace 27 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 29:00.30 |
| 28 | Meghan MaskePlace 28 · Grade 10 · Edwardsville (Metro-East Lutheran) | 10 | Edwardsville (Metro-East Lutheran) | 29:58.05 |
| 29 | Emilia MalcombPlace 29 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 30:03.38 |
| 30 | Aliana BushPlace 30 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 30:19.32 |
| 31 | Mackenzie HallPlace 31 · Grade 10 · Centralia (Christ Our Rock Lutheran) | 10 | Centralia (Christ Our Rock Lutheran) | 45:55.27 |
