| 1 | Lily KamadulskiPlace 1 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 18:56.20 |
| 2 | Brenley KellyPlace 2 · Grade 11 · Jerseyville (Jersey) | 11 | Jerseyville (Jersey) | 19:00.50 |
| 3 | Morgan GreenwaldPlace 3 · Grade 10 · Highland | 10 | Highland | 19:28.50 |
| 4 | Maggie SchwabPlace 4 · Grade 10 · Litchfield | 10 | Litchfield | 19:35.50 |
| 5 | Rachael ReckmannPlace 5 · Grade 11 · Highland | 11 | Highland | 19:45.40 |
| 6 | Claire SkaffPlace 6 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 19:47.20 |
| 7 | Josie KircherPlace 7 · Grade 11 · Highland | 11 | Highland | 19:48.00 |
| 8 | Grace JansenPlace 8 · Grade 11 · Belleville (Althoff Catholic) | 11 | Belleville (Althoff Catholic) | 19:54.90 |
| 9 | Gianna StassiPlace 9 · Grade 12 · Roxana | 12 | Roxana | 19:58.60 |
| 10 | Zorina BohannonPlace 10 · Grade 10 · Jacksonville | 10 | Jacksonville | 19:58.60 |
| 11 | Lucy DoylePlace 11 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 20:00.20 |
| 12 | Katie FentonPlace 12 · Grade 10 · Highland | 10 | Highland | 20:09.10 |
| 13 | Jordan HayesPlace 13 · Grade 9 · Mt. Vernon | 9 | Mt. Vernon | 20:19.80 |
| 14 | Kaylee GrandtPlace 14 · Grade 10 · Columbia | 10 | Columbia | 20:33.20 |
| 15 | Emma SavagePlace 15 · Grade 12 · Freeburg | 12 | Freeburg | 20:34.70 |
| 16 | Faith JansenPlace 16 · Grade 10 · Belleville (Althoff Catholic) | 10 | Belleville (Althoff Catholic) | 20:52.50 |
| 17 | Amelia JumperPlace 17 · Grade 10 · Jerseyville (Jersey) | 10 | Jerseyville (Jersey) | 21:01.10 |
| 18 | Elizabeth ClousePlace 18 · Grade 12 · Roxana | 12 | Roxana | 21:08.60 |
| 19 | Layla WheelerPlace 19 · Grade 9 · Mt. Vernon | 9 | Mt. Vernon | 21:12.60 |
| 20 | McKenzie JonesPlace 20 · Grade 12 · Glen Carbon (Father McGivney) | 12 | Glen Carbon (Father McGivney) | 21:21.40 |
| 21 | Lucy KroeschenPlace 21 · Grade 11 · Mt. Vernon | 11 | Mt. Vernon | 21:23.10 |
| 22 | Lily RainsPlace 22 · Grade 11 · Mt. Vernon | 11 | Mt. Vernon | 21:25.90 |
| 23 | Abigail (Abby) AyerPlace 23 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 21:28.60 |
| 24 | Charline VianinPlace 24 · Grade 12 · Alton | 12 | Alton | 21:32.00 |
| 25 | Madison MarshallPlace 25 · Grade 10 · Freeburg | 10 | Freeburg | 21:38.90 |
| 26 | Ashlyn TebbePlace 26 · Grade 9 · Breese (Central) | 9 | Breese (Central) | 21:42.10 |
| 27 | Sara BookPlace 27 · Grade 9 · Breese (Central) | 9 | Breese (Central) | 21:44.10 |
| 28 | Cecilia MuehlPlace 28 · Grade 11 · Columbia | 11 | Columbia | 21:45.20 |
| 29 | Iylie HarrisPlace 29 · Grade 12 · Mt. Vernon | 12 | Mt. Vernon | 22:00.50 |
| 30 | Leah MahtaniPlace 30 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 22:01.60 |
| 31 | Autumn GoffPlace 31 · Grade 9 · Freeburg | 9 | Freeburg | 22:01.80 |
| 32 | Abbie RussellPlace 32 · Grade 12 · Mt. Vernon | 12 | Mt. Vernon | 22:06.60 |
| 33 | Charley FunkPlace 33 · Grade 11 · Waterloo | 11 | Waterloo | 22:10.30 |
| 34 | Rilynn YounkerPlace 34 · Grade 12 · Litchfield | 12 | Litchfield | 22:10.40 |
| 35 | Ava LockPlace 35 · Grade 12 · Belleville (Althoff Catholic) | 12 | Belleville (Althoff Catholic) | 22:13.10 |
| 36 | Eliana MuehlPlace 36 · Grade 10 · Columbia | 10 | Columbia | 22:17.50 |
| 37 | Hazel HeadPlace 37 · Grade 10 · Freeburg | 10 | Freeburg | 22:17.60 |
| 38 | Marion HemmerPlace 38 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 22:24.40 |
| 39 | Libbey GibbsPlace 39 · Grade 9 · Litchfield | 9 | Litchfield | 22:26.60 PR |
| 40 | Elizabeth MollPlace 40 · Grade 9 · Glen Carbon (Father McGivney) | 9 | Glen Carbon (Father McGivney) | 22:33.00 |
| 41 | Emma LappePlace 41 · Grade 9 · Breese (Central) | 9 | Breese (Central) | 22:33.20 |
| 42 | Kennedy BaxPlace 42 · Grade 12 · Mt. Vernon | 12 | Mt. Vernon | 22:38.20 |
| 43 | Savannah ClinePlace 43 · Grade 10 · Roxana | 10 | Roxana | 22:45.60 |
| 44 | Lily WallochPlace 44 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 22:48.90 |
| 45 | Rowan PassmorePlace 45 · Grade 12 · Highland | 12 | Highland | 22:50.60 |
| 46 | Tinley BirkenkampPlace 46 · Grade 9 · Litchfield | 9 | Litchfield | 22:56.70 |
| 47 | Adelaide CookPlace 47 · Grade 10 · Highland | 10 | Highland | 22:57.80 |
| 48 | Moira KruegerPlace 48 · Grade 11 · Edwardsville (Metro-East Lutheran) | 11 | Edwardsville (Metro-East Lutheran) | 22:58.00 |
| 49 | Melia BowmanPlace 49 · Grade 9 · Highland | 9 | Highland | 23:05.10 |
| 50 | Sam ChristPlace 50 · Grade 10 · Freeburg | 10 | Freeburg | 23:05.60 |
| 51 | Devyn MartinoPlace 51 · Grade 11 · Jacksonville | 11 | Jacksonville | 23:09.20 |
| 52 | Bailey Schallenberg-DeckerPlace 52 · Grade 12 · Roxana | 12 | Roxana | 23:10.60 |
| 53 | Abby ShermanPlace 53 · Grade 12 · Freeburg | 12 | Freeburg | 23:15.20 |
| 54 | Georgia CurtisPlace 54 · Grade 11 · Columbia | 11 | Columbia | 23:23.60 |
| 55 | Leah NewtonPlace 55 · Grade 11 · Roxana | 11 | Roxana | 23:25.10 |
| 56 | Maple SuchomskiPlace 56 · Grade 9 · Highland | 9 | Highland | 23:26.30 |
| 57 | Anna MoorePlace 57 · Grade 11 · Glen Carbon (Father McGivney) | 11 | Glen Carbon (Father McGivney) | 23:44.00 |
| 58 | Leah McClellandPlace 58 · Grade 10 · Columbia | 10 | Columbia | 23:44.20 |
| 59 | Jerra VanausdollPlace 59 · Grade 12 · Jerseyville (Jersey) | 12 | Jerseyville (Jersey) | 23:50.60 |
| 60 | Elizabeth HatleyPlace 60 · Grade 9 · Highland | 9 | Highland | 23:51.70 PR |
| 61 | Ella HenrichsPlace 61 · Grade 11 · Breese (Central) | 11 | Breese (Central) | 23:54.40 |
| 62 | Hallie ProughPlace 62 · Grade 10 · Alton | 10 | Alton | 23:56.00 |
| 63 | Morgan InlowPlace 63 · Grade 9 · Highland | 9 | Highland | 24:04.40 |
| 64 | Mackenzie MinnerPlace 64 · Grade 11 · Wood River (East Alton-W.R.) | 11 | Wood River (East Alton-W.R.) | 24:07.60 |
| 65 | Lilly McClurePlace 65 · Grade 12 · Freeburg | 12 | Freeburg | 24:14.60 |
| 66 | Livy JacksonPlace 66 · Grade 10 · Breese (Central) | 10 | Breese (Central) | 24:20.90 |
| 67 | Agnes HemmerPlace 67 · Grade 9 · Edwardsville (Metro-East Lutheran) | 9 | Edwardsville (Metro-East Lutheran) | 24:21.40 |
| 68 | Caroline CardinalPlace 68 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 24:37.40 |
| 69 | Riley BurtonPlace 69 · Grade 9 · Columbia | 9 | Columbia | 24:40.90 |
| 70 | Anna CaughranPlace 70 · Grade 11 · Alton | 11 | Alton | 24:50.80 |
| 71 | Evelyn SchultzPlace 71 · Grade 9 · Belleville (Althoff Catholic) | 9 | Belleville (Althoff Catholic) | 24:57.50 |
| 72 | Lydia AndersonPlace 72 · Grade 11 · Waterloo | 11 | Waterloo | 24:59.30 |
| 73 | Ava DewittPlace 73 · Grade 9 · Jacksonville | 9 | Jacksonville | 25:16.40 |
| 74 | Natalie JohnsonPlace 74 · Grade 11 · Columbia | 11 | Columbia | 25:22.70 |
| 75 | Katherine FitzgeraldPlace 75 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 25:31.00 |
| 76 | Haley HelfrichPlace 76 · Grade 10 · Freeburg | 10 | Freeburg | 25:40.90 |
| 77 | Ava VenhausPlace 77 · Grade 12 · Trenton (Wesclin) | 12 | Trenton (Wesclin) | 25:50.40 |
| 78 | Kinsey MaschhoffPlace 78 · Grade 9 · Freeburg | 9 | Freeburg | 26:00.20 |
| 79 | Lacie HillPlace 79 · Grade 10 · Freeburg | 10 | Freeburg | 26:07.20 |
| 80 | Jordyn KellerPlace 80 · Grade 11 · Waterloo | 11 | Waterloo | 26:11.50 |
| 81 | Mercie LaxtonPlace 81 · Grade 9 · Columbia | 9 | Columbia | 26:22.20 |
| 82 | Phoebe RangePlace 82 · Grade 10 · Columbia | 10 | Columbia | 26:31.00 |
| 83 | Rylee HemkenPlace 83 · Grade 9 · Litchfield | 9 | Litchfield | 26:34.50 |
| 84 | Ava FilePlace 84 · Grade 12 · Greenville | 12 | Greenville | 27:51.20 |
| 85 | Alice SternauPlace 85 · Grade 10 · Columbia | 10 | Columbia | 27:58.60 |
| 86 | Rory SpeidelPlace 86 · Grade 12 · Jerseyville (Jersey) | 12 | Jerseyville (Jersey) | 27:59.00 |
| 87 | Selah FieldPlace 87 · Grade 12 · Greenville | 12 | Greenville | 28:12.50 |
| 88 | Ami ParsonsPlace 88 · Grade 10 · Wood River (East Alton-W.R.) | 10 | Wood River (East Alton-W.R.) | 28:22.10 |
| 89 | Haylee BrownPlace 89 · Grade 10 · Alton | 10 | Alton | 28:46.30 |
| 90 | Ashlyn WhelanPlace 90 · Grade 11 · Waterloo | 11 | Waterloo | 29:01.80 |
| 91 | Melinda RoblesPlace 91 · Grade 11 · Jerseyville (Jersey) | 11 | Jerseyville (Jersey) | 30:18.90 |
| 92 | Ayda EggemeyerPlace 92 · Grade 11 · Waterloo | 11 | Waterloo | 30:33.20 |
