| 1 | Layla HolladayPlace 1 · Grade 11 · Socastee | 11 | Socastee | 22:03.86 |
| 2 | Emma JohnsonPlace 2 · Grade 8 · Socastee | 8 | Socastee | 22:12.98 |
| 3 | Harleigh SullivanPlace 3 · Grade 9 · Aynor | 9 | Aynor | 22:31.67 |
| 4 | Allie SpaederPlace 4 · Grade 9 · Providence Athletic Club | 9 | Providence Athletic Club | 22:46.01 |
| 5 | Reagan ReedPlace 5 · Grade 12 · Hartsville | 12 | Hartsville | 22:51.26 |
| 6 | Rokel SandersPlace 6 · Grade 12 · Wilson | 12 | Wilson | 23:00.87 |
| 7 | Lucy FrechettePlace 7 · Grade 9 · Socastee | 9 | Socastee | 23:09.82 |
| 8 | Havah MarionPlace 8 · Grade 10 · Providence Athletic Club | 10 | Providence Athletic Club | 23:30.00 |
| 9 | Paige MayhewPlace 9 · Grade 12 · Socastee | 12 | Socastee | 23:30.76 PR |
| 10 | Stary SamuelPlace 10 · Grade 12 · Wilson | 12 | Wilson | 23:41.98 PR |
| 11 | Hayden RobinsonPlace 11 · Grade 12 · Wilson | 12 | Wilson | 23:46.48 PR |
| 12 | Ry'leigh MorrisPlace 12 · Grade 8 · Lamar | 8 | Lamar | 23:49.82 PR |
| 13 | Kaiya AndersonPlace 13 · Grade 8 · Hartsville | 8 | Hartsville | 23:56.04 PR |
| 14 | Annie GorePlace 14 · Grade 10 · Providence Athletic Club | 10 | Providence Athletic Club | 23:56.30 PR |
| 15 | Brielle FonteneauPlace 15 · Grade 9 · Hartsville | 9 | Hartsville | 24:01.22 PR |
| 16 | Naomi MarionPlace 16 · Grade 12 · Providence Athletic Club | 12 | Providence Athletic Club | 24:01.27 |
| 17 | Olivia FreePlace 17 · Grade 10 · Socastee | 10 | Socastee | 24:03.42 PR |
| 18 | Rebecca FrentiPlace 18 · Grade 10 · Socastee | 10 | Socastee | 24:07.35 |
| 19 | Leah CaldwellPlace 19 · Grade 11 · Providence Athletic Club | 11 | Providence Athletic Club | 24:26.68 |
| 20 | Charlotte SnyderPlace 20 · Grade 8 · Providence Athletic Club | 8 | Providence Athletic Club | 24:28.76 |
| 21 | Mackenzie SturkiePlace 21 · Grade 7 · Lamar | 7 | Lamar | 24:37.18 PR |
| 22 | Rachel SchoemanPlace 22 · Grade 12 · Governors Sch For Science & Math | 12 | Governors Sch For Science & Math | 24:49.82 |
| 23 | Taylor WilsonPlace 23 · Grade 12 · Socastee | 12 | Socastee | 24:59.12 |
| 24 | Maylee BrownPlace 24 · Grade 9 · South Florence | 9 | South Florence | 25:06.38 PR |
| 25 | Julie ShealyPlace 25 · Grade 11 · Providence Athletic Club | 11 | Providence Athletic Club | 25:08.65 PR |
| 26 | Abbygail SmithPlace 26 · Grade 12 · Hartsville | 12 | Hartsville | 25:11.60 |
| 27 | Lilli-eun RobinsonPlace 27 · Grade 11 · Governors Sch For Science & Math | 11 | Governors Sch For Science & Math | 25:31.60 |
| 28 | Grey WinterbottomPlace 28 · Grade 8 · Aynor | 8 | Aynor | 25:44.24 PR |
| 29 | Alexandra CompherPlace 29 · Grade 11 · Governors Sch For Science & Math | 11 | Governors Sch For Science & Math | 25:50.45 PR |
| 30 | Gabby MendiolaPlace 30 · Grade 12 · Lamar | 12 | Lamar | 25:55.93 |
| 31 | Stokes FieldsPlace 31 · Grade 10 · South Florence | 10 | South Florence | 25:59.07 |
| 32 | Josephine MacePlace 32 · Grade 12 · Governors Sch For Science & Math | 12 | Governors Sch For Science & Math | 26:08.89 PR |
| 33 | Bridget DorselPlace 33 · Grade 10 · Hartsville | 10 | Hartsville | 26:11.05 |
| 34 | Ava TynerPlace 34 · Grade 11 · South Florence | 11 | South Florence | 26:21.23 |
| 35 | Aubrie StricklandPlace 35 · Grade 9 · Aynor | 9 | Aynor | 26:23.35 PR |
| 36 | Shakira EppsPlace 36 · Grade 10 · Wilson | 10 | Wilson | 26:29.72 |
| 37 | Rebecca AndersonPlace 37 · Grade 10 · Hartsville | 10 | Hartsville | 26:30.41 PR |
| 38 | Mercy RussellPlace 38 · Grade 7 · Covenant Classical Christian | 7 | Covenant Classical Christian | 26:35.59 PR |
| 39 | Aleksa BradfordPlace 39 · Grade 9 · Aynor | 9 | Aynor | 26:54.33 PR |
| 40 | Linh WattsPlace 40 · Grade 11 · Governors Sch For Science & Math | 11 | Governors Sch For Science & Math | 27:09.63 PR |
| 41 | Amaris BurnesPlace 41 · Grade 7 · Wilson | 7 | Wilson | 27:45.34 PR |
| 42 | Audrey SowellPlace 42 · Grade 8 · Lamar | 8 | Lamar | 27:50.21 PR |
| 43 | Taylor KinlawPlace 43 · Grade 7 · Wilson | 7 | Wilson | 29:02.61 |
| 44 | Amelia SteinmetzPlace 44 · Grade 12 · South Florence | 12 | South Florence | 29:35.23 |
| 45 | Aylssa SaleebyPlace 45 · Grade 10 · Hartsville | 10 | Hartsville | 30:03.73 |
| 46 | Abigail BrewerPlace 46 · Grade 9 · South Florence | 9 | South Florence | 32:17.12 |
| 47 | Phoenix LilleyPlace 47 · Grade 10 · Lamar | 10 | Lamar | 35:31.93 PR |
