| 1 | Hayden NeaglePlace 1 · Grade 10 · Seton Catholic | 10 | Seton Catholic | 18:45.63 |
| 2 | Aubrey NeaglePlace 2 · Grade 10 · Seton Catholic | 10 | Seton Catholic | 20:24.10 |
| 3 | Noah MillerPlace 3 · Grade 9 · Herron | 9 | Herron | 20:35.44 |
| 4 | Avery HoffmanPlace 4 · Grade 11 · Herron | 11 | Herron | 20:51.69 |
| 5 | Rya GrilleyPlace 5 · Grade 12 · Herron | 12 | Herron | 21:19.59 |
| 6 | Kylie RitzPlace 6 · Grade 12 · Park Tudor | 12 | Park Tudor | 21:36.22 |
| 7 | Lauren LoPlace 7 · Grade 12 · Park Tudor | 12 | Park Tudor | 21:56.02 |
| 8 | Lilian RochPlace 8 · Grade 9 · University | 9 | University | 22:11.69 |
| 9 | Annabella ThompsonPlace 9 · Grade 12 · Herron | 12 | Herron | 22:15.05 |
| 10 | Raya StennisPlace 10 · Grade 11 · University | 11 | University | 22:22.05 |
| 11 | Gwyneth BeckPlace 11 · Grade 9 · Park Tudor | 9 | Park Tudor | 22:48.04 |
| 12 | Olivia GholsonPlace 12 · Grade 10 · Bethesda Christian | 10 | Bethesda Christian | 22:53.55 |
| 13 | Lilly BlanchardPlace 13 · Grade 11 · Bethesda Christian | 11 | Bethesda Christian | 22:55.74 |
| 14 | Kaia BarronPlace 14 · Grade 12 · University | 12 | University | 23:24.28 |
| 15 | Everly FisherPlace 15 · Grade 12 · Herron | 12 | Herron | 23:32.99 |
| 16 | Bella GroothuisPlace 16 · Grade 12 · Indianapolis Shortridge | 12 | Indianapolis Shortridge | 23:34.05 |
| 17 | Sydney RitzPlace 17 · Grade So · Park Tudor | So | Park Tudor | 23:38.19 |
| 18 | Helen SinsabaughPlace 18 · Grade 9 · Herron | 9 | Herron | 23:39.35 |
| 19 | Sam FladelandPlace 19 · Grade 11 · Herron | 11 | Herron | 23:41.82 |
| 20 | Celia McDermottPlace 20 · Grade 12 · Herron | 12 | Herron | 23:46.97 PR |
| 21 | Kiana HastingsPlace 21 · Grade 10 · Herron | 10 | Herron | 23:56.53 |
| 22 | Navya ShahPlace 22 · Grade 12 · University | 12 | University | 24:00.12 |
| 23 | Maggie MiddletonPlace 23 · Grade 10 · Seton Catholic | 10 | Seton Catholic | 24:13.00 |
| 24 | Delaney BlairPlace 24 · Grade 11 · University | 11 | University | 24:49.93 |
| 25 | Kamila Torres RodriguezPlace 25 · Grade So · Park Tudor | So | Park Tudor | 25:06.99 |
| 26 | Jarzen CeliaPlace 26 · Grade 12 · Indianapolis Shortridge | 12 | Indianapolis Shortridge | 25:11.24 |
| 27 | Lucia RoblesPlace 27 · Grade 9 · Indianapolis Shortridge | 9 | Indianapolis Shortridge | 25:40.55 |
| 28 | Rachel LouisPlace 28 · Grade So · Park Tudor | So | Park Tudor | 25:48.98 |
| 29 | Addison HunleyPlace 29 · Grade 12 · Indianapolis Shortridge | 12 | Indianapolis Shortridge | 25:55.33 |
| 30 | Helen ErnstPlace 30 · Grade 11 · University | 11 | University | 27:10.39 |
| 31 | Maxine SteenslandPlace 31 · Grade 9 · University | 9 | University | 27:16.17 |
| 32 | Brynn KaryPlace 32 · Grade 12 · University | 12 | University | 27:24.21 |
| 33 | Gwen HawkPlace 33 · Grade 11 · Indianapolis Shortridge | 11 | Indianapolis Shortridge | 27:50.52 |
| 34 | Lila MorrisonPlace 34 · Grade So · Park Tudor | So | Park Tudor | 28:07.74 |
| 35 | Lucy ByersPlace 35 · Grade 10 · Herron | 10 | Herron | 28:23.74 |
| 36 | Piper SpiethPlace 36 · Grade 9 · University | 9 | University | 28:29.56 |
| 37 | Bridget BlackPlace 37 · Grade 9 · Herron | 9 | Herron | 28:31.18 |
| 38 | Kate BradburyPlace 38 · Grade 9 · International School of Indiana | 9 | International School of Indiana | 28:41.76 |
| 39 | Rita FischerPlace 39 · Grade 9 · University | 9 | University | 28:46.86 |
| 40 | Grace JohnsonPlace 40 · Grade 11 · Indianapolis Shortridge | 11 | Indianapolis Shortridge | 29:16.14 |
| 41 | Madeline ZyromskiPlace 41 · Grade 12 · University | 12 | University | 29:28.31 |
| 42 | Jayla MosleyPlace 42 · Grade 10 · Anderson Preparatory Academy | 10 | Anderson Preparatory Academy | 29:29.09 PR |
| 43 | Sophia SmithPlace 43 · Grade 11 · Indianapolis Shortridge | 11 | Indianapolis Shortridge | 29:35.87 PR |
| 44 | Avery TrieuPlace 44 · Grade 9 · University | 9 | University | 29:50.09 |
| 45 | Hannah NewsomPlace 45 · Grade 12 · Herron | 12 | Herron | 29:56.58 |
| 46 | Serena BrownPlace 46 · Grade 12 · Indianapolis Shortridge | 12 | Indianapolis Shortridge | 31:19.49 |
| 47 | Morgan HumrichouserPlace 47 · Grade 10 · Park Tudor | 10 | Park Tudor | 32:17.22 |
| 48 | Zoe ZelenakPlace 48 · Grade 9 · University | 9 | University | 33:03.78 PR |
| 49 | Natalie MurrayPlace 49 · Grade 9 · University | 9 | University | 33:49.46 |
| 50 | Wilhelmina WilsonPlace 50 · Grade 12 · Indianapolis Shortridge | 12 | Indianapolis Shortridge | 34:26.35 |
| 51 | Kaylee JohnsonPlace 51 · Grade 12 · Indianapolis Shortridge | 12 | Indianapolis Shortridge | 35:21.74 |
