| 1 | Brianna ReillyPlace 1 · Grade 9 · Harrisburg | 9 | Harrisburg | 17:30.69 |
| 2 | Hannah GenrichPlace 2 · Grade 10 · Harrisburg | 10 | Harrisburg | 18:10.66 |
| 3 | Kaylie KuehlPlace 3 · Grade 12 · Brookings | 12 | Brookings | 18:39.17 |
| 4 | Nora YoumansPlace 4 · Grade 8 · Yankton | 8 | Yankton | 18:52.82 PR |
| 5 | Grace McElroyPlace 5 · Grade 10 · Watertown | 10 | Watertown | 18:59.92 |
| 6 | Eloise ScharnbergPlace 6 · Grade 8 · Harrisburg | 8 | Harrisburg | 19:13.79 |
| 7 | Kaitlyn HarrisPlace 7 · Grade 11 · Brookings | 11 | Brookings | 19:19.60 |
| 8 | Allie NovstrupPlace 8 · Grade 10 · Aberdeen Central | 10 | Aberdeen Central | 19:21.13 |
| 9 | Avery WuestewaldPlace 9 · Grade 8 · Yankton | 8 | Yankton | 19:27.19 PR |
| 10 | Kenley FritzPlace 10 · Grade 9 · Harrisburg | 9 | Harrisburg | 19:34.13 |
| 11 | Verity KocmickPlace 11 · Grade 12 · Harrisburg | 12 | Harrisburg | 19:40.86 |
| 12 | Madison MoorePlace 12 · Grade 9 · Harrisburg | 9 | Harrisburg | 19:48.59 |
| 13 | Abby JohannesonPlace 13 · Grade 11 · Yankton | 11 | Yankton | 19:49.93 |
| 14 | Kate McElroyPlace 14 · Grade 12 · Watertown | 12 | Watertown | 19:51.01 |
| 15 | Lilly GerlachPlace 15 · Grade 8 · Watertown | 8 | Watertown | 19:55.44 |
| 16 | Jordyn JohnsonPlace 16 · Grade 12 · Brookings | 12 | Brookings | 19:59.25 |
| 17 | Peyton BeatchPlace 17 · Grade 8 · Brandon Valley | 8 | Brandon Valley | 20:16.17 |
| 18 | Grace BialasPlace 18 · Grade 11 · Tea Area | 11 | Tea Area | 20:20.09 |
| 19 | Aubrey CooleyPlace 19 · Grade 8 · Brookings | 8 | Brookings | 20:27.57 |
| 20 | Rilyn JacksonPlace 20 · Grade 11 · Yankton | 11 | Yankton | 20:30.15 |
| 21 | Gracen GieglingPlace 21 · Grade 12 · Harrisburg | 12 | Harrisburg | 20:33.91 |
| 22 | Olivia AndersonPlace 22 · Grade 11 · Watertown | 11 | Watertown | 20:43.56 |
| 23 | Kalla FoersterPlace 23 · Grade 11 · Brookings | 11 | Brookings | 20:45.78 |
| 24 | Taylor BoehnkePlace 24 · Grade 10 · Tea Area | 10 | Tea Area | 20:52.79 |
| 25 | Khloe CochranPlace 25 · Grade 12 · Aberdeen Central | 12 | Aberdeen Central | 20:54.84 PR |
| 26 | Maisie MogardPlace 26 · Grade 11 · Brookings | 11 | Brookings | 21:00.15 |
| 27 | Nina GabrielPlace 27 · Grade 12 · Harrisburg | 12 | Harrisburg | 21:02.71 |
| 28 | Rykr BillingsPlace 28 · Grade 10 · Brookings | 10 | Brookings | 21:12.87 |
| 29 | Londyn SchroederPlace 29 · Grade 12 · Mitchell | 12 | Mitchell | 21:14.80 |
| 30 | Ailee JohnsonPlace 30 · Grade 10 · Harrisburg | 10 | Harrisburg | 21:15.41 |
| 31 | Evie NovstrupPlace 31 · Grade 10 · Aberdeen Central | 10 | Aberdeen Central | 21:23.82 |
| 32 | Gretchen CurtisPlace 32 · Grade 10 · Tea Area | 10 | Tea Area | 21:29.31 |
| 33 | Kapri HergesPlace 33 · Grade 8 · Mitchell | 8 | Mitchell | 21:30.97 |
| 34 | Sydney CavenPlace 34 · Grade 9 · Pierre T.F. Riggs | 9 | Pierre T.F. Riggs | 21:32.97 |
| 35 | Grace ListPlace 35 · Grade 12 · Watertown | 12 | Watertown | 21:38.21 |
| 36 | Hanlee SeykoraPlace 36 · Grade 10 · Harrisburg | 10 | Harrisburg | 21:41.49 |
| 37 | Logan CastlePlace 37 · Grade 11 · Tea Area | 11 | Tea Area | 21:45.43 |
| 38 | Ella VogtPlace 38 · Grade 7 · Yankton | 7 | Yankton | 21:48.22 PR |
| 39 | Lily MeyerPlace 39 · Grade 12 · Huron | 12 | Huron | 21:50.95 |
| 40 | Lola UnderbergPlace 40 · Grade 10 · Tea Area | 10 | Tea Area | 22:03.72 |
| 41 | Skylar LawsonPlace 41 · Grade 8 · Mitchell | 8 | Mitchell | 22:03.90 |
| 42 | Jayda JensenPlace 42 · Grade 11 · Watertown | 11 | Watertown | 22:05.64 |
| 43 | Nevaeh GutenkaufPlace 43 · Grade 8 · Pierre T.F. Riggs | 8 | Pierre T.F. Riggs | 22:13.55 |
| 44 | Summer SpanglerPlace 44 · Grade 9 · Brandon Valley | 9 | Brandon Valley | 22:16.57 |
| 45 | Sarah OedekovenPlace 45 · Grade 9 · Pierre T.F. Riggs | 9 | Pierre T.F. Riggs | 22:16.83 |
| 46 | Addison ReichlingPlace 46 · Grade 12 · Watertown | 12 | Watertown | 22:19.12 |
| 47 | Lily DeSchepperPlace 47 · Grade 9 · Pierre T.F. Riggs | 9 | Pierre T.F. Riggs | 22:21.57 |
| 48 | Nora PesterPlace 48 · Grade 12 · Huron | 12 | Huron | 22:37.11 |
| 49 | Hannah KochPlace 49 · Grade 10 · Brandon Valley | 10 | Brandon Valley | 22:50.87 |
| 50 | Abby HillesonPlace 50 · Grade 11 · Tea Area | 11 | Tea Area | 23:02.71 |
| 51 | Lacey TaylorPlace 51 · Grade 9 · Yankton | 9 | Yankton | 23:11.76 |
| 52 | Aubrie BrendselPlace 52 · Grade 11 · Brandon Valley | 11 | Brandon Valley | 23:13.52 |
| 53 | Grace PreszlerPlace 53 · Grade 9 · Aberdeen Central | 9 | Aberdeen Central | 23:18.56 |
| 54 | Lily SwansonPlace 54 · Grade 11 · Huron | 11 | Huron | 23:30.27 |
| 55 | Averi GerfenPlace 55 · Grade 12 · Mitchell | 12 | Mitchell | 23:31.11 |
| 56 | Olivia SchneeklothPlace 56 · Grade 9 · Brandon Valley | 9 | Brandon Valley | 23:42.64 |
| 57 | Imani CaballeroPlace 57 · Grade 9 · Yankton | 9 | Yankton | 23:46.38 |
| 58 | Grace ChapmanPlace 58 · Grade 10 · Tea Area | 10 | Tea Area | 23:50.20 |
| 59 | Genesis AndersonPlace 59 · Grade 7 · Watertown | 7 | Watertown | 23:50.39 |
| 60 | Bree CochranPlace 60 · Grade 10 · Aberdeen Central | 10 | Aberdeen Central | 24:02.45 |
| 61 | Lilly FloodPlace 61 · Grade 12 · Aberdeen Central | 12 | Aberdeen Central | 24:09.69 |
| 62 | Elsa SchiferlPlace 62 · Grade 12 · Aberdeen Central | 12 | Aberdeen Central | 24:22.16 |
| 63 | Hailey WeaverPlace 63 · Grade 8 · Pierre T.F. Riggs | 8 | Pierre T.F. Riggs | 24:22.31 |
| 64 | Haley CahoyPlace 64 · Grade 10 · Aberdeen Central | 10 | Aberdeen Central | 24:27.92 |
| 65 | Sydnie PischelPlace 65 · Grade 9 · Mitchell | 9 | Mitchell | 24:29.38 |
| 66 | Caroline WiesePlace 66 · Grade 8 · Brandon Valley | 8 | Brandon Valley | 24:39.93 |
| 67 | Kemrey DeDeynePlace 67 · Grade 7 · Huron | 7 | Huron | 24:44.40 PR |
| 68 | Kamryn SantiPlace 68 · Grade 12 · Brandon Valley | 12 | Brandon Valley | 25:01.86 |
| 69 | Brynlie HoferPlace 69 · Grade 7 · Huron | 7 | Huron | 25:17.96 PR |
| 70 | Isabel WipfPlace 70 · Grade 8 · Huron | 8 | Huron | 25:18.03 PR |
| 71 | Evelyn CoughlinPlace 71 · Grade 9 · Pierre T.F. Riggs | 9 | Pierre T.F. Riggs | 25:38.90 |
| 72 | Natalie HyronimusPlace 72 · Grade 10 · Tea Area | 10 | Tea Area | 25:57.49 |
| 73 | Ella KampsPlace 73 · Grade 10 · Tea Area | 10 | Tea Area | 26:14.52 |
| 74 | Kendall ClaytonPlace 74 · Grade 12 · Brandon Valley | 12 | Brandon Valley | 27:05.44 |
