| 1. | Tess ReyesPlace 1. · Grade 10 · Algonquin Regional | 10 | Algonquin Regional | 2:21.36a | 10 |
| 1. | Gianna MastromatteoPlace 1. · Grade 12 · St Peter-Marian | 12 | St Peter-Marian | 2:22.89a | 10 |
| 2. | Kaitlyn RoffmanPlace 2. · Grade 10 · Littleton | 10 | Littleton | 2:23.31a | 8 |
| 2. | Emily DesmondPlace 2. · Grade 12 · Westborough | 12 | Westborough | 2:23.54a | 8 |
| 3. | Erin GiugnoPlace 3. · Grade 12 · Marlborough | 12 | Marlborough | 2:24.29a | 6 |
| 1. | Kaylin CieslukPlace 1. · Grade 12 · Oakmont Regional | 12 | Oakmont Regional | 2:26.48a | 10 |
| 4. | Ella LemieuxPlace 4. · Grade 10 · Nashoba Reg | 10 | Nashoba Reg | 2:26.94a | 4 |
| 3. | Emma HartzelPlace 3. · Grade 11 · Littleton | 11 | Littleton | 2:27.13a | 6 |
| 2. | Sophia CampbellPlace 2. · Grade 10 · Tyngsborough | 10 | Tyngsborough | 2:27.87a | 8 |
| 5. | Reagan GilloolyPlace 5. · Grade 10 · Shrewsbury | 10 | Shrewsbury | 2:28.39a | 2 |
| 6. | Emma WhiteheadPlace 6. · Grade 10 · Shepherd Hill Reg | 10 | Shepherd Hill Reg | 2:28.70a PR | 1 |
| 7. | Abigail ValleyPlace 7. · Grade 9 · Wachusett Regional | 9 | Wachusett Regional | 2:28.81a | — |
| 8. | Noelle BassPlace 8. · Grade 10 · Marlborough | 10 | Marlborough | 2:30.27a | — |
| 3. | Alysse CarpenterPlace 3. · Grade 12 · Leicester | 12 | Leicester | 2:31.23a PR | 6 |
| 9. | Maddi DohertyPlace 9. · Grade 12 · Tantasqua Regional Senior | 12 | Tantasqua Regional Senior | 2:31.56a | — |
| 10. | Abigail ThorupPlace 10. · Grade 10 · Algonquin Regional | 10 | Algonquin Regional | 2:32.20a PR | — |
| 4. | Anna NortonPlace 4. · Grade 10 · Ayer Shirley Regional | 10 | Ayer Shirley Regional | 2:33.45a | 4 |
| 11. | Allie KovacsPlace 11. · Grade 10 · Nashoba Reg | 10 | Nashoba Reg | 2:34.29a | — |
| 12. | Tiana MunizPlace 12. · Grade 10 · Fitchburg | 10 | Fitchburg | 2:34.39a PR | — |
| 4. | Jessika AntinoriPlace 4. · Grade 11 · Lunenburg | 11 | Lunenburg | 2:34.84a PR | 4 |
| 5. | Abby CelataPlace 5. · Grade 11 · Narragansett Regional | 11 | Narragansett Regional | 2:36.42a | 2 |
| 13. | Katherine SouthardPlace 13. · Grade 10 · Shrewsbury | 10 | Shrewsbury | 2:37.34a | — |
| 5. | Gabriella MaiaPlace 5. · Grade 8 · Lunenburg | 8 | Lunenburg | 2:39.20a | 2 |
| 14. | Emmalyn SteelePlace 14. · Grade 9 · Wachusett Regional | 9 | Wachusett Regional | 2:39.67a PR | — |
| 15. | Riley BurnhamPlace 15. · Grade 9 · Wachusett Regional | 9 | Wachusett Regional | 2:39.87a | — |
| 6. | Abigail KeaglePlace 6. · Grade 10 · Quabbin Regional | 10 | Quabbin Regional | 2:40.85a PR | 1 |
| 6. | Callie WiedlePlace 6. · Grade 8 · Narragansett Regional | 8 | Narragansett Regional | 2:41.47a | 1 |
| 16. | Maeve O'MalleyPlace 16. · Grade 10 · Leominster | 10 | Leominster | 2:41.94a PR | — |
| 7. | Kelsey RenoPlace 7. · Grade 9 · Millbury Memorial | 9 | Millbury Memorial | 2:42.82a PR | — |
| 7. | Hanna PicardPlace 7. · Grade 12 · Whitinsville Christian | 12 | Whitinsville Christian | 2:43.52a | — |
| 8. | Sarah MaplePlace 8. · Grade 10 · St Peter-Marian | 10 | St Peter-Marian | 2:44.20a PR | — |
| 9. | Heather FontainePlace 9. · Grade 11 · Quaboag Regional Middle/High | 11 | Quaboag Regional Middle/High | 2:45.40a | — |
| 10. | Violet CobbPlace 10. · Grade 10 · Maynard | 10 | Maynard | 2:45.43a PR | — |
| 17. | Keira BergeronPlace 17. · Grade 10 · Tantasqua Regional Senior | 10 | Tantasqua Regional Senior | 2:46.24a | — |
| 8. | Lauren RainonePlace 8. · Grade 10 · Blackstone-Millville Reg | 10 | Blackstone-Millville Reg | 2:46.54a | — |
