| 1 | Gia LeonePlace 1 · Grade SO · Waccamaw | SO | Waccamaw | 20:09.36 |
| 2 | Alice FranckePlace 2 · Grade JR · Waccamaw | JR | Waccamaw | 20:11.23 |
| 3 | Candace KiefferPlace 3 · Grade JR · Unattached | JR | Unattached | 20:22.18 |
| 4 | Katie PouPlace 4 · Grade SR · Nation Ford | SR | Nation Ford | 20:26.02 |
| 5 | Hannah VroonPlace 5 · Grade 9 · James Island | 9 | James Island | 20:32.18 |
| 6 | Kaiti NuttPlace 6 · Grade FR · Unattached | FR | Unattached | 20:34.94 |
| 7 | Amelia MaughanPlace 7 · Grade JR · Pandemic Distance Pr | JR | Pandemic Distance Pr | 20:37.11 |
| 8 | Carina BurdickPlace 8 · Grade JR · Irmo | JR | Irmo | 20:50.69 |
| 9 | Anna Margaret LoftusPlace 9 · Grade SO · Waccamaw | SO | Waccamaw | 21:11.81 |
| 10 | Ansley ArchuletaPlace 10 · Grade SR · Nation Ford | SR | Nation Ford | 21:19.99 |
| 11 | Kaylanna BurroughsPlace 11 · Grade 7 · Wilson | 7 | Wilson | 21:27.12 |
| 12 | Kate HooverPlace 12 · Grade SO · Ben Lippen | SO | Ben Lippen | 21:28.75 |
| 13 | Alyssa LomorielloPlace 13 · Grade 9 · Dutch Fork | 9 | Dutch Fork | 21:28.81 |
| 14 | Caroline TimmonsPlace 14 · Grade 9 · Cardinal Newman | 9 | Cardinal Newman | 21:46.23 |
| 15 | Chloe DavisPlace 15 · Grade SO · Ben Lippen | SO | Ben Lippen | 21:52.63 |
| 16 | Amelia CarsonPlace 16 · Grade SR · James Island | SR | James Island | 21:52.91 |
| 17 | Kirra BorgPlace 17 · Grade 8 · James Island | 8 | James Island | 21:55.95 |
| 18 | Alexis VanderveldePlace 18 · Grade SR · Dutch Fork | SR | Dutch Fork | 22:07.18 |
| 19 | Lily JenkinsPlace 19 · Grade SO · Irmo | SO | Irmo | 22:15.82 |
| 20 | Hannah WilliamsPlace 20 · Grade SO · Irmo | SO | Irmo | 22:19.70 |
| 21 | Correll TribbeyPlace 21 · Grade SO · Aquinas | SO | Aquinas | 22:26.01 |
| 22 | Taylor WashingtonPlace 22 · Grade 8 · Dutch Fork | 8 | Dutch Fork | 22:32.91 |
| 23 | Ella JeffreyPlace 23 · Grade SO · Northside Christian | SO | Northside Christian | 22:35.46 |
| 24 | Riley BeyerPlace 24 · Grade SO · Ben Lippen | SO | Ben Lippen | 22:36.37 |
| 25 | Esther SuPlace 25 · Grade 9 · Irmo | 9 | Irmo | 22:36.45 |
| 26 | Elise HillPlace 26 · Grade SR · Dutch Fork | SR | Dutch Fork | 22:44.11 |
| 27 | Anna KellyPlace 27 · Grade 7 · Blythewood | 7 | Blythewood | 22:45.35 |
| 28 | Mia RoyallPlace 28 · Grade 9 · Nation Ford | 9 | Nation Ford | 22:57.95 |
| 29 | Adria KahrePlace 29 · Grade 8 · Nation Ford | 8 | Nation Ford | 22:58.64 |
| 30 | Rachael NeillPlace 30 · Grade JR · Waccamaw | JR | Waccamaw | 22:58.65 |
| 31 | Dawson RichardsonPlace 31 · Grade 8 · Waccamaw | 8 | Waccamaw | 22:58.66 |
| 32 | Sophia HendersonPlace 32 · Grade SR · Irmo | SR | Irmo | 23:02.73 |
| 33 | Lila JenningsPlace 33 · Grade 7 · Waccamaw | 7 | Waccamaw | 23:03.96 |
| 34 | Lola GanttPlace 34 · Grade 8 · Irmo | 8 | Irmo | 23:08.01 |
| 35 | Abigail GoppPlace 35 · Grade 9 · Dutch Fork | 9 | Dutch Fork | 23:08.35 |
| 36 | Kate TimmonsPlace 36 · Grade 7 · Cardinal Newman | 7 | Cardinal Newman | 23:13.53 |
| 37 | Gabby JourdainPlace 37 · Grade 9 · Calhoun Academy | 9 | Calhoun Academy | 23:17.25 |
| 38 | Emily BergPlace 38 · Grade SR · Cardinal Newman | SR | Cardinal Newman | 23:25.17 |
| 39 | Olivia CoxPlace 39 · Cardinal Newman | — | Cardinal Newman | 23:26.16 |
| 40 | Ella FataPlace 40 · Grade SR · Waccamaw | SR | Waccamaw | 23:28.59 |
| 41 | Mackenzie MeierPlace 41 · Grade SR · Dutch Fork | SR | Dutch Fork | 23:35.15 |
| 42 | Tania WilsonPlace 42 · Grade JR · Carolina Liberty Run | JR | Carolina Liberty Run | 23:41.56 |
| 43 | Madison HagerPlace 43 · Grade SR · Nation Ford | SR | Nation Ford | 23:41.80 |
| 44 | Bayleigh WomackPlace 44 · Grade SO · Northside Christian | SO | Northside Christian | 23:46.87 |
| 45 | M.K. HuddlestonPlace 45 · Grade SO · James Island | SO | James Island | 23:48.60 |
| 46 | Sarah DayhuffPlace 46 · Grade JR · Cardinal Newman | JR | Cardinal Newman | 23:49.49 |
| 47 | Maureen OrtizPlace 47 · Grade SO · Dutch Fork | SO | Dutch Fork | 23:56.33 |
| 48 | Chloe McDanielPlace 48 · Grade SR · Wilson | SR | Wilson | 23:57.30 |
| 49 | Caroline WinslowPlace 49 · Grade SR · Cardinal Newman | SR | Cardinal Newman | 24:05.09 |
| 50 | Jordyn BattlePlace 50 · Grade 8 · Nation Ford | 8 | Nation Ford | 24:18.60 |
| 51 | Kaitlynn FordPlace 51 · Grade JR · Northside Christian | JR | Northside Christian | 24:24.41 |
| 52 | Ree Williams ZollerPlace 52 · Grade SO · Ben Lippen | SO | Ben Lippen | 24:25.24 |
| 53 | Simone JosephPlace 53 · Grade JR · Cardinal Newman | JR | Cardinal Newman | 24:39.78 |
| 54 | Alisa HaasePlace 54 · Grade 9 · Cane Bay | 9 | Cane Bay | 24:49.09 |
| 55 | Miku PitmanPlace 55 · Grade JR · Nation Ford | JR | Nation Ford | 24:54.97 |
| 56 | Ainsley AllenPlace 56 · Grade JR · Brookland Cayce | JR | Brookland Cayce | 25:07.03 |
| 57 | Carlisle MillerPlace 57 · Grade 9 · James Island | 9 | James Island | 25:07.90 |
| 58 | Egypt HowardPlace 58 · Grade JR · Cane Bay | JR | Cane Bay | 25:09.75 |
| 59 | Natalie WeaverPlace 59 · Grade SR · Irmo | SR | Irmo | 25:12.38 |
| 60 | Julia BeebePlace 60 · Grade SR · James Island | SR | James Island | 25:15.66 |
| 61 | Kennedy AgnewPlace 61 · Grade SO · Cane Bay | SO | Cane Bay | 25:16.84 |
| 62 | Caroline EasterlingPlace 62 · Grade 9 · Ben Lippen | 9 | Ben Lippen | 25:19.89 |
| 63 | callie MorrisPlace 63 · Grade SO · Ben Lippen | SO | Ben Lippen | 25:23.58 |
| 64 | Kira MartinPlace 64 · Grade 9 · Cane Bay | 9 | Cane Bay | 25:23.62 |
| 65 | Casey MccarsonPlace 65 · Grade JR · Calhoun Academy | JR | Calhoun Academy | 25:23.76 |
| 66 | Brooke BarkerPlace 66 · Grade 9 · Blythewood | 9 | Blythewood | 25:35.01 |
| 67 | Madison SchofieldPlace 67 · Grade JR · Carolina Liberty Run | JR | Carolina Liberty Run | 25:36.93 |
| 68 | Ashley NiuPlace 68 · Grade 9 · Unattached | 9 | Unattached | 25:50.63 |
| 69 | Natalie WalkePlace 69 · Grade 9 · Northside Christian | 9 | Northside Christian | 25:55.30 |
| 70 | Lucia KirklandPlace 70 · Grade SO · Ben Lippen | SO | Ben Lippen | 26:00.37 |
| 71 | Brinlee RisenmayPlace 71 · Grade JR · Carolina Liberty Run | JR | Carolina Liberty Run | 26:00.77 |
| 72 | Alyssa BabinPlace 72 · Grade SO · Cane Bay | SO | Cane Bay | 26:01.63 |
| 73 | Ali AldridgePlace 73 · Grade SR · Wilson | SR | Wilson | 26:01.82 |
| 74 | Caitlin HollingsworthPlace 74 · Grade JR · Calhoun Academy | JR | Calhoun Academy | 26:26.99 |
| 75 | Colleen StevensonPlace 75 · Grade SO · Aquinas | SO | Aquinas | 26:29.07 |
| 76 | Kiersten PricePlace 76 · Grade JR · Wilson | JR | Wilson | 27:07.89 |
| 77 | Leigh DetaloPlace 77 · Grade SO · Wilson | SO | Wilson | 27:13.25 |
| 78 | Jacqueline CongerPlace 78 · Grade 8 · Cane Bay | 8 | Cane Bay | 27:14.42 |
| 79 | Kara PerkinsPlace 79 · Grade JR · Cane Bay | JR | Cane Bay | 27:18.14 |
| 80 | Sophie WatsonPlace 80 · Grade SR · Wilson | SR | Wilson | 27:35.39 |
| 81 | Eva PendletonPlace 81 · Grade 9 · Blythewood | 9 | Blythewood | 27:38.75 |
| 82 | Jenycis SherwoodPlace 82 · Grade JR · Blythewood | JR | Blythewood | 28:06.06 |
| 83 | Paulina HalusPlace 83 · Grade SR · Wilson | SR | Wilson | 28:11.15 |
| 84 | Victoria TajellePlace 84 · Grade SO · Ridge View | SO | Ridge View | 28:28.73 |
| 85 | Victoria ThreattPlace 85 · Covenant Classical | — | Covenant Classical | 28:45.22 |
| 86 | Phina RabacaPlace 86 · Grade 9 · Blythewood | 9 | Blythewood | 28:51.49 |
| 87 | Victoria ThomasPlace 87 · Grade 9 · Northside Christian | 9 | Northside Christian | 29:33.64 |
| 88 | Lexi BrownPlace 88 · Grade SR · Aquinas | SR | Aquinas | 29:40.87 |
| 89 | Emma Kate SwygertPlace 89 · Grade 8 · Northside Christian | 8 | Northside Christian | 29:43.37 |
| 90 | Landry MintonPlace 90 · Grade JR · Aquinas | JR | Aquinas | 29:58.02 |
| 91 | Tessa WarePlace 91 · Grade SR · Blythewood | SR | Blythewood | 29:59.38 |
| 92 | Kaedance QuayePlace 92 · Grade JR · Ridge View | JR | Ridge View | 30:30.80 |
| 93 | Isabella TaylorPlace 93 · Grade SO · Ridge View | SO | Ridge View | 30:44.14 |
| 94 | Sunasia MorganPlace 94 · Grade SO · Ridge View | SO | Ridge View | 30:46.17 |
| 95 | Lexie LeonPlace 95 · Grade SO · Carolina Liberty Run | SO | Carolina Liberty Run | 31:33.73 |
| 96 | Morgan HowardPlace 96 · Grade 8 · Northside Christian | 8 | Northside Christian | 32:07.77 |
| 97 | Phoebe FischerPlace 97 · Grade SR · Blythewood | SR | Blythewood | 32:26.28 |
| 98 | Kayla EzzellePlace 98 · Grade 8 · Brookland Cayce | 8 | Brookland Cayce | 33:01.33 |
| 99 | Tamya StewartPlace 99 · Grade 9 · Ridge View | 9 | Ridge View | 34:17.91 |
| 100 | Kenyanna SmithPlace 100 · Grade SO · Ridge View | SO | Ridge View | 34:21.41 |
| 101 | Sydney SpringsPlace 101 · Grade JR · Brookland Cayce | JR | Brookland Cayce | 37:39.66 |
| 102 | Sierra TweedPlace 102 · Grade 9 · Brookland Cayce | 9 | Brookland Cayce | 39:08.46 |
| 103 | Raeleigh HaferPlace 103 · Grade 9 · Brookland Cayce | 9 | Brookland Cayce | 39:36.75 |
| 104 | Hannah OsmerPlace 104 · Grade JR · Brookland Cayce | JR | Brookland Cayce | 40:42.33 |