| 1 | Brooklyn WilliamsonPlace 1 · Grade 12 · Belton-Honea Path | 12 | Belton-Honea Path | 19:35.56 | 1 |
| 2 | Dawson RichardsonPlace 2 · Grade 12 · Waccamaw | 12 | Waccamaw | 19:50.65 | 2 |
| 3 | Megan MadiganPlace 3 · Grade 12 · Waccamaw | 12 | Waccamaw | 20:00.10 | 3 |
| 4 | Mckenna OwnbeyPlace 4 · Grade 7 · Waccamaw | 7 | Waccamaw | 20:00.79 PR | 4 |
| 5 | Jude AyersPlace 5 · Grade 9 · Hanahan | 9 | Hanahan | 20:09.69 | 5 |
| 6 | Katelyn BussellPlace 6 · Grade 10 · Hanahan | 10 | Hanahan | 20:19.34 | 6 |
| 7 | Elona DarbyPlace 7 · Grade 9 · Palmetto | 9 | Palmetto | 20:29.70 | 7 |
| 8 | Colby DelamielleurePlace 8 · Grade 8 · Hanahan | 8 | Hanahan | 20:32.35 | 8 |
| 9 | Eliza RoyPlace 9 · Grade 12 · Christ Church Episcopal | 12 | Christ Church Episcopal | 20:34.63 | 9 |
| 10 | Betsy DorrietyPlace 10 · Grade 11 · Belton-Honea Path | 11 | Belton-Honea Path | 20:48.22 | 10 |
| 11 | Savannah PruittPlace 11 · Grade 8 · Belton-Honea Path | 8 | Belton-Honea Path | 20:55.99 | 11 |
| 12 | Charlotte ShewPlace 12 · Grade 8 · Christ Church Episcopal | 8 | Christ Church Episcopal | 20:58.17 | 12 |
| 13 | Lexi DelamielleurePlace 13 · Grade 10 · Hanahan | 10 | Hanahan | 20:59.70 PR | 13 |
| 14 | Kayla SheedyPlace 14 · Grade 12 · Waccamaw | 12 | Waccamaw | 21:06.81 | 14 |
| 15 | Lola GanttPlace 15 · Grade 12 · Hanahan | 12 | Hanahan | 21:06.86 | 15 |
| 16 | Elara TAYLORPlace 16 · Mountain View Prep H | — | Mountain View Prep H | 21:10.78 | 16 |
| 17 | Margaret MullenPlace 17 · Grade 10 · Christ Church Episcopal | 10 | Christ Church Episcopal | 21:14.97 | 17 |
| 18 | Lindsay LattimerPlace 18 · Grade 12 · Waccamaw | 12 | Waccamaw | 21:24.82 | 18 |
| 19 | Emily HuntPlace 19 · Grade 11 · Belton-Honea Path | 11 | Belton-Honea Path | 21:36.71 | 19 |
| 20 | Lila JenningsPlace 20 · Grade 11 · Waccamaw | 11 | Waccamaw | 21:41.70 | 20 |
| 21 | Stella SatterfieldPlace 21 · Grade 7 · Palmetto | 7 | Palmetto | 21:46.15 | 21 |
| 22 | Kinsley BlackPlace 22 · Grade 8 · Belton-Honea Path | 8 | Belton-Honea Path | 21:48.08 | 22 |
| 23 | Iris FulkPlace 23 · Grade 8 · Belton-Honea Path | 8 | Belton-Honea Path | 21:48.12 | 23 |
| 24 | Faith CrawfordPlace 24 · Grade 12 · Pendleton | 12 | Pendleton | 21:49.79 | 24 |
| 25 | Maggie SmithPlace 25 · Grade 11 · Pendleton | 11 | Pendleton | 21:51.84 PR | 25 |
| 26 | Charleigh TroutmanPlace 26 · Grade 11 · Pendleton | 11 | Pendleton | 21:53.07 | 26 |
| 27 | Elise FosterPlace 27 · Grade 12 · Pendleton | 12 | Pendleton | 22:14.11 | 27 |
| 28 | Italia RICHESPlace 28 · Mountain View Prep H | — | Mountain View Prep H | 22:27.24 | 28 |
| 29 | Maya KryshtalowychPlace 29 · Grade 10 · Fox Creek | 10 | Fox Creek | 22:32.74 | 29 |
| 30 | Kylie WillisPlace 30 · Grade 12 · Pendleton | 12 | Pendleton | 22:38.41 | 30 |
| 31 | Peyton PeduzziPlace 31 · Grade 10 · Fox Creek | 10 | Fox Creek | 22:39.60 | 31 |
| 32 | Kendal MasonPlace 32 · Grade 11 · Waccamaw | 11 | Waccamaw | 22:44.66 | 32 |
| 33 | Lacey BurdettePlace 33 · Grade 8 · Crescent | 8 | Crescent | 22:44.99 | 33 |
| 34 | Ella WilcoxPlace 34 · Grade 10 · Crescent | 10 | Crescent | 22:49.79 | 34 |
| 35 | Isadora ApplePlace 35 · Grade 10 · Christ Church Episcopal | 10 | Christ Church Episcopal | 23:01.94 | 35 |
| 36 | Brinley StevickPlace 36 · Grade 7 · Hanahan | 7 | Hanahan | 23:04.06 | 36 |
| 37 | Olive DixonPlace 37 · Grade 10 · Fox Creek | 10 | Fox Creek | 23:10.88 | 37 |
| 38 | Mary McdonaldPlace 38 · Grade 10 · Christ Church Episcopal | 10 | Christ Church Episcopal | 23:16.77 | 38 |
| 39 | Della HollingsworthPlace 39 · Grade 8 · Pendleton | 8 | Pendleton | 23:19.53 | 39 |
| 40 | Alivia WilliamsPlace 40 · Grade 9 · Palmetto | 9 | Palmetto | 23:22.41 | 40 |
| 41 | Audrey LEWISPlace 41 · Mountain View Prep H | — | Mountain View Prep H | 23:25.44 | 41 |
| 42 | Natalie McAbeePlace 42 · Grade 8 · Crescent | 8 | Crescent | 23:30.12 | 42 |
| 43 | Evana PartainPlace 43 · Grade 11 · Crescent | 11 | Crescent | 23:38.69 | 43 |
| 44 | Serena TAYLORPlace 44 · Mountain View Prep H | — | Mountain View Prep H | 23:53.42 | 44 |
| 45 | Addison BarryPlace 45 · Grade 10 · Hanahan | 10 | Hanahan | 24:01.56 PR | 45 |
| 46 | Daija AlexanderPlace 46 · Grade 11 · Pendleton | 11 | Pendleton | 24:14.84 | 46 |
| 47 | Madelyn BrothertonPlace 47 · Grade 12 · Christ Church Episcopal | 12 | Christ Church Episcopal | 24:20.41 | 47 |
| 48 | Alyssa WalkerPlace 48 · Grade 9 · Crescent | 9 | Crescent | 24:24.79 | 48 |
| 49 | Leilani MONROYPlace 49 · Mountain View Prep H | — | Mountain View Prep H | 24:31.53 | 49 |
| 50 | Brinkley ArthurPlace 50 · Grade 7 · Palmetto | 7 | Palmetto | 24:44.42 | 50 |
| 51 | Ruth ButcherPlace 51 · Grade 12 · Christ Church Episcopal | 12 | Christ Church Episcopal | 24:54.04 | 51 |
| 52 | Sophia BurgessPlace 52 · Grade 9 · Palmetto | 9 | Palmetto | 24:55.96 PR | 52 |
| 53 | Harleigh SullivanPlace 53 · Grade 8 · Aynor | 8 | Aynor | 25:02.92 | 53 |
| 54 | Kaitlyn ThompsonPlace 54 · Grade 12 · Crescent | 12 | Crescent | 25:10.91 | 54 |
| 55 | Lily EidellPlace 55 · Grade 11 · Fox Creek | 11 | Fox Creek | 25:14.64 | 55 |
| 56 | Marley MillwoodPlace 56 · Grade 12 · Aynor | 12 | Aynor | 25:32.34 | 56 |
| 57 | Carson BARNETTEPlace 57 · Mountain View Prep H | — | Mountain View Prep H | 25:54.41 | 57 |
| 58 | Lashondra BrownPlace 58 · Grade 11 · Fox Creek | 11 | Fox Creek | 26:13.51 | 58 |
| 59 | Kailyn EibenPlace 59 · Grade 10 · Aynor | 10 | Aynor | 26:20.52 | 59 |
| 60 | Tiffany WillisPlace 60 · Grade 11 · West Oak | 11 | West Oak | 26:37.49 PR | 0 |
| 61 | Mckinley JohnsonPlace 61 · Grade 8 · Aynor | 8 | Aynor | 28:17.26 | 60 |
| 62 | Julieona WeatherfordPlace 62 · Grade 8 · Aynor | 8 | Aynor | 28:30.09 | 61 |
| 63 | Megan StoutPlace 63 · Grade 11 · West Oak | 11 | West Oak | 31:08.78 | 0 |
| 64 | Jordy GilesPlace 64 · Grade 9 · Aynor | 9 | Aynor | 32:38.98 | 62 |
| 65 | Sarah DennyPlace 65 · Grade 8 · West Oak | 8 | West Oak | 32:39.02 | 0 |
