| 1 | Emberlie GoinsPlace 1 · Grade 10 · Troy (Triad) | 10 | Troy (Triad) | 19:18.60 |
| 2 | Samantha CookPlace 2 · Grade 12 · Oakville | 12 | Oakville | 19:58.50 PR |
| 3 | Elcee WatersPlace 3 · Grade 11 · Quincy (Notre Dame) | 11 | Quincy (Notre Dame) | 20:14.60 |
| 4 | Lily KamadulskiPlace 4 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 20:43.30 |
| 5 | Leila HiattPlace 5 · Grade 9 · Troy (Triad) | 9 | Troy (Triad) | 21:35.80 |
| 6 | Cecelia ThompsonPlace 6 · Grade 12 · Oakville | 12 | Oakville | 21:36.80 PR |
| 7 | Makena SteelePlace 7 · Grade 11 · Troy (Triad) | 11 | Troy (Triad) | 21:45.60 |
| 8 | Ava GarbePlace 8 · Grade 9 · Lebanon | 9 | Lebanon | 21:55.90 |
| 9 | Ryelan JudiscakPlace 9 · Grade 12 · Collinsville | 12 | Collinsville | 22:01.50 |
| 10 | Daniya HillPlace 10 · Grade 12 · East St. Louis | 12 | East St. Louis | 22:11.10 |
| 11 | Addison DurbinPlace 11 · Grade 11 · Lebanon | 11 | Lebanon | 22:26.70 |
| 12 | Sophie PerryPlace 12 · Grade 11 · O'Fallon | 11 | O'Fallon | 22:31.80 |
| 13 | Rachael ReckmannPlace 13 · Grade 11 · Highland | 11 | Highland | 22:39.20 |
| 14 | Katie FentonPlace 14 · Grade 10 · Highland | 10 | Highland | 22:39.30 |
| 15 | Josie KircherPlace 15 · Grade 11 · Highland | 11 | Highland | 22:39.50 |
| 16 | Morgan GreenwaldPlace 16 · Grade 10 · Highland | 10 | Highland | 22:39.60 |
| 17 | Abby DeteringPlace 17 · Grade 11 · Mascoutah | 11 | Mascoutah | 22:50.20 |
| 18 | Leah MahtaniPlace 18 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 23:03.30 |
| 19 | Ja'Kayla AtkinsPlace 19 · Grade 11 · East St. Louis | 11 | East St. Louis | 23:04.90 |
| 20 | Olivia WileyPlace 20 · Grade 11 · Bethalto (Civic Memorial) | 11 | Bethalto (Civic Memorial) | 23:13.80 |
| 21 | Lillie WoodPlace 21 · Grade 11 · Bethalto (Civic Memorial) | 11 | Bethalto (Civic Memorial) | 23:32.40 |
| 22 | Emmalyn SmithPlace 22 · Grade 12 · Quincy (Notre Dame) | 12 | Quincy (Notre Dame) | 23:35.10 |
| 23 | Harper DiehlPlace 23 · Grade 9 · Troy (Triad) | 9 | Troy (Triad) | 23:37.10 |
| 24 | Maple SuchomskiPlace 24 · Grade 9 · Highland | 9 | Highland | 23:45.40 |
| 25 | Emma TatePlace 25 · Grade 12 · O'Fallon | 12 | O'Fallon | 24:03.80 |
| 26 | Abcde ClimacoPlace 26 · Grade 11 · Mascoutah | 11 | Mascoutah | 24:06.30 |
| 27 | Mya WalkerPlace 27 · Grade 12 · Bethalto (Civic Memorial) | 12 | Bethalto (Civic Memorial) | 24:08.80 |
| 28 | Adelaide CookPlace 28 · Grade 10 · Highland | 10 | Highland | 24:12.10 |
| 29 | Melia BowmanPlace 29 · Grade 9 · Highland | 9 | Highland | 24:13.30 |
| 30 | Tileah GibbsPlace 30 · Grade 10 · Cahokia | 10 | Cahokia | 24:14.10 |
| 31 | Caroline CardinalPlace 31 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 24:15.00 |
| 32 | Addison BruttoPlace 32 · Grade 10 · Belleville (West) | 10 | Belleville (West) | 24:15.00 |
| 33 | Katherine FitzgeraldPlace 33 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 24:23.30 |
| 34 | Joey NguyenPlace 34 · Grade 12 · O'Fallon | 12 | O'Fallon | 24:25.40 |
| 35 | Leah HolbrookPlace 35 · Grade 10 · Quincy (Notre Dame) | 10 | Quincy (Notre Dame) | 24:31.70 |
| 36 | Savannah SeedallPlace 36 · Grade 11 · O'Fallon | 11 | O'Fallon | 24:34.80 |
| 37 | Elizabeth HatleyPlace 37 · Grade 9 · Highland | 9 | Highland | 24:47.00 |
| 38 | Audrey PaynePlace 38 · Grade 10 · Collinsville | 10 | Collinsville | 24:51.50 |
| 39 | Campbell PlassmanPlace 39 · Grade 12 · O'Fallon | 12 | O'Fallon | 24:58.20 |
| 40 | Addison AllenPlace 40 · Grade 11 · Lebanon | 11 | Lebanon | 25:11.80 |
| 41 | Olivia WalshPlace 41 · Grade 9 · Oakville | 9 | Oakville | 25:15.80 PR |
| 42 | Katherine MontgomeryPlace 42 · Grade 10 · O'Fallon | 10 | O'Fallon | 25:19.20 |
| 43 | Meghan ReynoldsPlace 43 · Grade 11 · Oakville | 11 | Oakville | 25:21.90 PR |
| 44 | Audrey LinkPlace 44 · Grade 10 · O'Fallon | 10 | O'Fallon | 25:23.30 |
| 45 | Alyssa McCallaPlace 45 · Grade 10 · Troy (Triad) | 10 | Troy (Triad) | 25:50.00 |
| 46 | Trinity WilliamsPlace 46 · Grade 9 · O'Fallon | 9 | O'Fallon | 25:52.10 |
| 47 | Peyton ReckmannPlace 47 · Grade 9 · O'Fallon | 9 | O'Fallon | 26:05.90 |
| 48 | Tara SanghaviPlace 48 · Grade 12 · O'Fallon | 12 | O'Fallon | 26:07.20 |
| 49 | Skylar PacePlace 49 · Grade 11 · Collinsville | 11 | Collinsville | 26:14.40 |
| 50 | Grace AndrewsPlace 50 · Grade 10 · O'Fallon | 10 | O'Fallon | 26:15.90 |
| 51 | Peyton HamiltonPlace 51 · Grade 12 · Mascoutah | 12 | Mascoutah | 26:21.50 |
| 52 | Morgan InlowPlace 52 · Grade 9 · Highland | 9 | Highland | 26:23.50 |
| 53 | Brielle FosterPlace 53 · Grade 10 · East St. Louis | 10 | East St. Louis | 26:31.60 |
| 54 | Shirlores StewartPlace 54 · Grade 12 · East St. Louis | 12 | East St. Louis | 26:31.80 |
| 55 | Isabel StabinskyPlace 55 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 26:36.80 |
| 56 | Lily HoustonPlace 56 · Grade 9 · O'Fallon | 9 | O'Fallon | 26:43.70 |
| 57 | Anesa KelmendiPlace 57 · Grade 12 · Oakville | 12 | Oakville | 26:49.20 PR |
| 58 | Rowan PassmorePlace 58 · Grade 12 · Highland | 12 | Highland | 27:00.40 |
| 59 | Olivia BaileyPlace 59 · Grade 9 · Quincy (Notre Dame) | 9 | Quincy (Notre Dame) | 27:05.40 |
| 60 | Olivia WallacePlace 60 · Grade 9 · Bethalto (Civic Memorial) | 9 | Bethalto (Civic Memorial) | 27:10.20 |
| 61 | Madalynn WethingtonPlace 61 · Grade 9 · Centralia | 9 | Centralia | 27:17.20 |
| 62 | Lydia AndersonPlace 62 · Grade 11 · Waterloo | 11 | Waterloo | 27:18.90 |
| 63 | Laina MelvinPlace 63 · Grade 10 · Oakville | 10 | Oakville | 27:21.30 PR |
| 64 | Adaleigh DonohoPlace 64 · Grade 12 · Centralia | 12 | Centralia | 27:29.70 |
| 65 | Madison HopperPlace 65 · Grade 11 · O'Fallon | 11 | O'Fallon | 27:32.70 |
| 66 | Esme MaloPlace 66 · Grade 10 · Collinsville | 10 | Collinsville | 27:35.00 |
| 67 | Piper EddyPlace 67 · Grade 10 · Quincy (Notre Dame) | 10 | Quincy (Notre Dame) | 27:36.10 |
| 68 | Kalea TavaresPlace 68 · Grade 12 · Belleville (West) | 12 | Belleville (West) | 27:45.10 |
| 69 | Demoriyanna MoorePlace 69 · Grade 9 · East St. Louis | 9 | East St. Louis | 27:48.60 |
| 70 | Gwynneth Van CleavePlace 70 · Grade 9 · Quincy (Notre Dame) | 9 | Quincy (Notre Dame) | 27:51.00 |
| 71 | Elizabeth MalfiPlace 71 · Grade 12 · Mascoutah | 12 | Mascoutah | 27:51.50 |
| 72 | Imogen KocaPlace 72 · Grade 9 · O'Fallon | 9 | O'Fallon | 27:57.50 |
| 73 | Nora Del MontePlace 73 · Grade 9 · Mascoutah | 9 | Mascoutah | 28:24.50 |
| 74 | Blakleigh HaubrichPlace 74 · Grade 9 · Quincy (Notre Dame) | 9 | Quincy (Notre Dame) | 29:16.70 |
| 75 | Morgan PrittsPlace 75 · Grade 11 · Quincy (Notre Dame) | 11 | Quincy (Notre Dame) | 29:21.20 |
| 76 | Sadie DemickPlace 76 · Grade 12 · Collinsville | 12 | Collinsville | 29:22.70 |
| 77 | Ashlyn WhelanPlace 77 · Grade 11 · Waterloo | 11 | Waterloo | 29:23.90 |
| 78 | Madison StokesPlace 78 · Grade 11 · O'Fallon | 11 | O'Fallon | 29:42.00 |
| 79 | Zoe HollowayPlace 79 · Grade 10 · Centralia | 10 | Centralia | 30:23.50 |
| 80 | Ayda EggemeyerPlace 80 · Grade 11 · Waterloo | 11 | Waterloo | 30:26.70 |
| 81 | Kyanna IvoryPlace 81 · Grade 9 · East St. Louis | 9 | East St. Louis | 30:31.20 |
| 82 | Kate StadlerPlace 82 · Grade 10 · Quincy (Notre Dame) | 10 | Quincy (Notre Dame) | 30:35.60 |
| 83 | Lainey RockwellPlace 83 · Grade 12 · Troy (Triad) | 12 | Troy (Triad) | 30:54.40 |
| 84 | Sofia WalkuskyPlace 84 · Grade 10 · O'Fallon | 10 | O'Fallon | 31:01.70 |
| 85 | Sarah BubbPlace 85 · Grade 11 · O'Fallon | 11 | O'Fallon | 31:18.20 |
| 86 | Adelyn MazanderPlace 86 · Grade 10 · Mascoutah | 10 | Mascoutah | 31:31.20 |
| 87 | Calista WebbPlace 87 · Grade 12 · Bethalto (Civic Memorial) | 12 | Bethalto (Civic Memorial) | 31:41.90 |
| 88 | Paige SmithPlace 88 · Grade 10 · Oakville | 10 | Oakville | 31:52.30 |
| 89 | Laniya JohnsonPlace 89 · Grade 9 · East St. Louis | 9 | East St. Louis | 31:57.30 |
| 90 | Taraji WigginsPlace 90 · Grade 11 · O'Fallon | 11 | O'Fallon | 32:29.90 |
| 91 | Keegan BrownPlace 91 · Grade 12 · Lebanon | 12 | Lebanon | 32:34.50 |
| 92 | Jasmine SpillerPlace 92 · Grade 11 · East St. Louis | 11 | East St. Louis | 33:33.80 |
| 93 | Damaya MoorePlace 93 · Grade 10 · East St. Louis | 10 | East St. Louis | 33:34.80 |
| 94 | Akari YoshidaPlace 94 · Grade 12 · Centralia | 12 | Centralia | 33:58.40 |
| 95 | Hannah RaycraftPlace 95 · Grade 10 · Alton (Marquette) | 10 | Alton (Marquette) | 34:32.30 |
| 96 | Rachel BessayPlace 96 · Grade 10 · Quincy (Notre Dame) | 10 | Quincy (Notre Dame) | 34:49.80 |
| 97 | Ly'Rah WatersPlace 97 · Grade 9 · East St. Louis | 9 | East St. Louis | 34:50.30 |
| 98 | Alexis BalsitisPlace 98 · Grade 11 · Collinsville | 11 | Collinsville | 35:43.70 |
| 99 | Aliana BushPlace 99 · Grade 9 · Maryville (M. Christian) | 9 | Maryville (M. Christian) | 36:16.30 |
| 100 | Emily BlivenPlace 100 · Grade 11 · Quincy (Notre Dame) | 11 | Quincy (Notre Dame) | 36:41.80 |
